FindA University Ltd Featured PhD Programmes
Xi’an Jiaotong-Liverpool University Featured PhD Programmes
Cardiff University Featured PhD Programmes

Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics

Faculty of Biological Sciences

About the Project

The World Health Organization (WHO) has declared antimicrobial drug resistance one of the greatest problems currently facing human health, and the situation is especially grave in the case of infections caused by bacterial pathogens. Compounding the issue, in the last 40 years only two structurally-novel antibacterial classes have been successfully developed for treating life-threatening bacterial infections.

The majority of our existing antibacterial armamentarium are microbial products; despite this, most antibacterial drug discovery programmes have abandoned the search for novel natural product antibiotics, favoring instead rational synthetic chemistry approaches which have yet to bear fruit.

The proposed studentship intends to utilize several innovative approaches to find and characterize novel antibiotic classes produced by micro-organisms, with a view to ultimately developing drugs active against multi-drug resistant bacterial pathogens such as Staphylococcus aureus and Pseudomonas aeruginosa.

Funding Notes

Please visit View Website


Hawkey, P. M. (2008). The growing burden of antimicrobial resistance. Journal of Antimicrobial Chemotherapy, 62 (Supplement 1), i1-i9. doi: 10.1093/jac/dkn241.
Talbot, G. H., Bradley, J., Edwards Jr., J. E., Gilbert, D., Scheld, M., Bartlett, J. G., et al. (2006). Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis., 42 (5), 657-68.

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here

The information you submit to University of Leeds will only be used by them or their data partners to deal with your enquiry, according to their privacy notice. For more information on how we use and store your data, please read our privacy statement.

* required field

Your enquiry has been emailed successfully

FindAPhD. Copyright 2005-2020
All rights reserved.