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Translation of novel polymer anti-bacterial coating to invasive medical devices used in the neonatal intensive care for high risk preterm infants

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  • Full or part time
    Prof M Alexander
    Assoc Prof D Sharkey
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Infections in premature babies are a leading cause of death, severe illness and are associated with poor long-term outcomes for survivors. Premature babies on intensive care units acquire these infections whilst in hospital, often from their life-supporting medical devices. This studentship will develop new coatings for these devices that resist bacterial colonisation and so reduce the risk of infection in these vulnerable babies. Based in the world-leading School of Pharmacy at the University of Nottingham, in partnership with academic neonatologists in the School of Medicine, the student will develop the new coatings, test them in vitro and in vivo, working closely with our industrial collaborator. There will be opportunities to train at the Harwell Research Complex learning cutting edge skills and spend time in the hospital environment, in a large research-active neonatal intensive care unit, to better understand the clinical need. This PhD will suit a highly ambitious science graduate, in the field of biology or chemistry, who wishes to undertake a truly translational clinical project with industry collaboration and training. It is expected that at the end of the project, the student will be well placed to secure follow-on funding for clinical trials and on-going development or commercialisation.

Industry partner Dr David Hampton, Camstent Ltd

Funding Notes

The studentships will commence in October 2020, and a stipend (£15,009 for 2019/20) and fee waiver for 3.5 years is available for UK applicants, plus research training support grant, travel and laptop allowance.

Fully funded studentships are available for UK applicants. EU applicants able to confirm that they have been resident in the UK for at least three years before October 2020 may also be eligible for a full award. EU students who are not able to prove that they meet the residency criteria may apply for a fees only award.

Interviews take place week commencing 17 February 2020.

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