The Experimental Pathology Group offers a PhD studentship in cancer biology, leading to a PhD degree from the University of Southampton.
The project aims to develop new approaches for cancer therapy, focusing on head & neck cancer, and exploring the role cancer-associated fibroblasts in regulating anti-tumour immunity and suppressing response to immunotherapy (eg. CJ Hanley et al., Nature Communications 2023; M Mellone et al., Cancer Research 2023; K Ford et al., Cancer Research 2020. Active research themes in the lab include characterising CAF phenotypes in human tumours using single cell sequencing, studying CAF interactions with immune cells and identifying novel strategies for therapeutic targeting of CAF-containing cancers. We enjoy close links with University Hospital Southampton and have a strong translational focus with excellent prospects for developing new therapies (eg. NCT05323656) and making a significant contribution to cancer treatment. The candidate will enjoy a vibrant multidisciplinary environment, take advantage of our ongoing collaborations with multiple industry collaborators and be provided with significant opportunities for excellent career development. The questions under investigation will require the use of a broad range of cell culture and molecular biology techniques, cell-based functional assays, single cell RNA sequencing and bioinformatics, analysis of human cancers and the use of mouse models.
The successful candidate is likely to have the following qualifications:
- A 1stor 2:1 degree in a relevant discipline and/or second degree with a related Masters.
Funding information:
Due to funding restrictions this position is only open to UK applicants. This PhD studentship is fully funded for four years by Cancer Research UK programme. The amount of stipend is £21,000.00 plus fees at UK residency rate with additional budget for laboratory costs.
Administrative contact and how to apply:
Please complete the University's online application form, which you can find at
https://student-selfservice.soton.ac.uk/BNNRPROD/bzsksrch.P_Login?pos=7205&majr=7205&term=202324
You should enter Professor Gareth Thomas as your proposed supervisor. To support your application provide an academic CV (including contact details of two referees), official academic transcripts and a personal statement (outlining your suitability for the studentship, what you hope to achieve from the PhD and your research experience to date).
Informal enquiries relating to the project or candidate suitability should be directed to Professor Gareth Thomas at [Email Address Removed]
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