About the Project
Training/techniques to be provided:
Computational biology, Quantitative proteome informatics, microRNA bioinformatics, R/python coding skills, knowledge of embryogenesis and development.
Candidates are expected to hold (or be about to obtain) a minimum upper second class honours degree (or equivalent) in a related area / subject, ideally in a bioscience or computational science. Candidates with experience in bioinformatics, computer science, software engineering or another related discipline are also encouraged to apply.
For international students we also offer a unique 4 year PhD programme that gives you the opportunity to undertake an accredited Teaching Certificate whilst carrying out an independent research project across a range of biological, medical and health sciences. For more information please visit http://www.internationalphd.manchester.ac.uk
As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Jarnuczak AF, Albornoz MG, Eyers CE, Grant CM, Hubbard SJ. A quantitative and temporal map of proteostasis during heat shock in Saccharomyces cerevisiae. Mol Omics. 2018 Feb 1;14(1):37-52. doi: 10.1039/c7mo00050b. Epub 2018 Jan 16. PubMed PMID: 29570196.
Lawless C, Holman SW, Brownridge P, Lanthaler K, Harman VM, Watkins R, Hammond DE, Miller RL, Sims PF, Grant CM, Eyers CE, Beynon RJ, Hubbard SJ. Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction
Monitoring. Mol Cell Proteomics. 2016 Apr;15(4):1309-22. doi:10.1074/mcp.M115.054288. Epub 2016 Jan 10. PubMed PMID: 26750110; PubMed Central PMCID: PMC4824857.
Ninova M, Ronshaugen M, Griffiths-Jones S. MicroRNA evolution, expression, and function during short germband development in Tribolium castaneum. Genome Res.2016 Jan;26(1):85-96. doi: 10.1101/gr.193367.115. Epub 2015 Oct 30. PubMed PMID: 26518483; PubMed Central PMCID: PMC4691753
Shimizu H, Woodcock SA, Wilkin MB, Trubenová B, Monk NA, Baron M. Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling. Cell. 2014 May 22;157(5):1160-74. doi: 10.1016/j.cell.2014.03.050. PubMed PMID: 24855951; PubMed Central PMCID: PMC4032575.
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