This PhD studentship is funded via an NIHR grant supporting collaboration between clinicians and scientists at St. James's hospital, Leeds, the Centre for Blood Research, Biology Department, York, and the Epidemiology and Cancer Statistics Group, York. This partnership brings together international leaders in clinical trials, translational science, and fundamental haemato-immunology to understand the role of blood and immune cells in bone marrow failure and leukaemia. Specifically, the successful student would be based at the University of York under the supervision of Professor Ian Hitchcock and Dr. Jillian Barlow with the aim of understanding the involvement of the thrombopoietin cytokine-receptor axis and innate lymphoid cells in these disease processes. To do this, the student will be expected to work with the Haematological Malignancy Diagnostic Service in Leeds, which alongside the related research network, tracks all patients diagnosed with haematological cancers and related disorders (about 2,500 diagnoses each year) across a catchment population of around 4 million people. The PhD project will therefore involve training in human tissue processing, flow cytometry, in vitro cell assays and tissue culture, and various molecular biology techniques in order to gain greater insight into the mechanisms underlying blood cancer.
The York Biomedical Research Institute at the University of York is committed to recruiting extraordinary future scientists regardless of age, ethnicity, gender, gender identity, disability, sexual orientation, religion/belief, marital status, pregnancy and maternity, or career pathway to date. We understand that commitment and excellence can be shown in many ways and have built our recruitment process to reflect this. We welcome applicants from all backgrounds, particularly those underrepresented in science, who have curiosity, creativity and a drive to learn new skills.