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Understanding the role of the tumour microenvironment in early disease development


Cancer Research UK Cambridge Institute

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Dr SE Bohndiek No more applications being accepted Funded PhD Project (Students Worldwide)

About the Project

Dr Sarah Bohndiek is head of a recently established, interdisciplinary research group that operates jointly between the Department of Physics and the Cancer Research UK Cambridge Institute. In the Physics laboratory, they develop and validate new imaging technologies. They currently focus on signal excitation in the visible and near infrared and aim to produce hyperspectral imaging methods with high sensitivity and specificity for clinical translation. In their CRUK CI laboratory, they combine these new developments in molecular imaging with preclinical disease models to better understand cancer progression and drug resistance. In particular, they are interested in the role of oxygen, including the presence, absence and metabolism of oxygen in tumour cells and surrounding blood vessels.
This project will apply novel imaging tools available within their laboratory to study the role of the tumour microenvironment in early disease development. Particular emphasis will be placed on stromal infiltration and angiogenesis. Imaging data will be validated using ex vivo gold standard methods.

The successful candidate will be based at the CRUK CI but will work closely with laboratory members based in Physics and other Departments in Cambridge. As a result, applicants should have excellent communication and team working skills, as well as an enthusiasm for interdisciplinary research and collaborations.
For up to date information about the research group, including their most recent publications, please see their website at:
http://www.bohndieklab.org
Applicants with previous experience of in vivo imaging or biomedical optics, for example during a Masters or Diploma degree, are particularly encouraged.


To apply, please send your academic CV and a covering letter as attachments to [Email Address Removed]
Your CV should include a list of the examinations taken at undergraduate level and if possible, your examination results. Also the names and contact details of two academic referees who have agreed to act on your behalf.
Your covering letter should explain why you wish to be considered for the studentship and which qualities and experience you will bring to the role. Please also state how you learned of the studentship.


Funding Notes

This project is funded by a Cancer Research UK studentship that includes full funding for University and College fees and a stipend of £19,000 per annum.
No nationality restrictions apply to Cancer Research UK funded studentships. Applications are invited from recent graduates or final year undergraduates who hold or expect to gain a first/upper second class degree (or equivalent) in a relevant subject from any recognised university worldwide.
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