This scholarship is funded by the Commonwealth Government to provide financial assistance to students during completion of a PhD and is aligned with recently awarded Category 1 NHMRC project grant. The scholarship provides a living stipend of $27,596 per annum (2019 rate, indexed annually), tuition fees, and Overseas Student Health Cover (OSHC).
Underlying principles of the gene therapy approach is outlined in: Coleman MA, Steptoe RJ. Induction of antigen-specific tolerance through hematopoietic stem cell-mediated gene therapy: the future for therapy of autoimmune disease? Autoimm Rev. (2012) 12(2):195-203. doi: 10.1016/j.autrev.2011.08.012
Other relevant references:
Brooks JF, Davies JM, Wells JW, Steptoe RJ. Re-educating the immune system in allergy: The potential for hematopoietic stem cell-mediated gene therapy. J Mol Med. (2017) 96(1), 21-30. doi: 10.1007/s00109-017-1611-8
Reeves PS, Rudraraju R, Wong FS, Hamilton-Williams EE, Steptoe RJ. APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice. Immunol Cell Biol. (2017) 95:765-774. doi: 10.1038/icb.2017.48
AL-Kouba J, Wilkinson A, Starkey MR, Rudraraju R, Werder R, Horvat JC, Law S-C, Liu T, Brooks JF, Hill GR, Phipps S, Davies, JM, Hansbro PM, Steptoe RJ. Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation. JCI Insight. (2017) 2(11):e85742. doi:10.1172/jci.insight.85742
Coleman MA, Jessup CF, Bridge JA, Overgaard NH, Penko D, Walters S, Borg DJ, Galea R, Forbes JM, Thomas R, Wells JW, Steptoe RJ. Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes. (2016) 65(5):1328–1340. doi: 10.2337/db15-1418
Steptoe RJ, Ritchie JM, Harrison LC. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J Clin Invest. (2003) 111:1357-1363.