What is the most clinically and cost-effective way of preventing type 2 diabetes? A systematic review, component network meta-analysis and economic evaluation of metformin and lifestyle interventions
Dr S Freeman
Prof N Cooper
Prof A Sutton
Prof K Khunti
No more applications being accepted
Competition Funded PhD Project (European/UK Students Only)
The National Institute for Health Research (NIHR) is the nation’s largest funder of health and care research and provides the people, facilities and technology that enables research to thrive. NIHR Applied Research Collaborations (ARCs) support applied health and care research that responds to, and meets, the needs of local populations and local health and care systems. The NIHR ARC East Midlands (EM) is one of 15 ARCs across England, part of a £135 million investment by the NIHR to improve the health and care of patients and the public.
The clinical themes ARC EM focuses on include: (i) Building Community Resilience and Enabling Independence; (ii) Mental Health and Wellbeing; (iii) Managing Multimorbidity. There are also three-cutting themes: (i) Translating and Implementing Sustainable Service Improvement; (ii) Ethnicity and Health Inequalities; (iii) Data2Health (Health Data Science).
The Data2Health theme will focus on methodological translation – ensuring that appropriate, innovative and fully evaluated methods are used to inform the design and analysis of ARC EM research studies. It will also ensure maximal use of existing large-scale linked data resources to address important questions for patients, the public and care services, both locally and nationally.
This PhD studentship will undertake a PhD project aligned to the aims of the Data2Health theme. Applicants should select one or more of the following projects when applying. Applicants are encouraged to contact the lead supervisor for more information on the projects.
This project will involve a systematic review and component network meta-analysis of randomised controlled trials of metformin, lifestyle interventions, combination of lifestyle with metformin and other relevant treatments for the prevention of type 2 diabetes followed by an economic evaluation to determine the cost-effectiveness of metformin and lifestyle interventions. Novel methods of visualising and communicating results of component network meta-analysis and cost-effectiveness models may also be explored.
Essential: UK Bachelor’s degree with at least 2:1 in a relevant subject (such as Maths or Statistics) or overseas equivalent.
Desirable: MSc Medical Statistics or similar postgraduate degree
University of Leicester English language requirements apply (where applicable).
How to apply
For further details, please see - https://le.ac.uk/study/research-degrees/funded-opportunities/hs-nihr-arc-east-midlands-2020
Funded by NIHR ARC East Midlands.
This 3 year Studentship provides:
UK/EU tuition fee waiver
Stipend at UKRI rates (£15,285 for 2020/21)