Postgrad LIVE! Study Fairs

Birmingham | Edinburgh | Liverpool | Sheffield | Southampton | Bristol

University of Birmingham Featured PhD Programmes
Coventry University Featured PhD Programmes
University College London Featured PhD Programmes
Birkbeck, University of London Featured PhD Programmes
University of Manchester Featured PhD Programmes

When do astrocytes contribute to the control of brain blood flow?

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

In order that the brain can function normally, it is essential that blood flow within the brain is well matched to neuronal metabolic demand. When neurons are active they send a message to the local vasculature to increase blood flow (a phenomenon called neurovascular coupling) and so increase the supply of nutrients: glucose and oxygen. This increase in blood flow and blood volume is the basis of non-invasive functional imaging signals such as BOLD fMRI. Understanding how different cells are involved in neurovascular coupling is important not only for understanding what functional imaging signals can tell us about the brain but also for helping us to understand what goes wrong in diseases where neurovascular coupling is altered. We will investigate which cells are involved in controlling brain blood flow under various conditions (e.g. in response to increased neuronal activity, in response to a physiological stimulus). Of particular interest are astrocytes, a supporting cell within the brain. Although astrocytes have been shown to modify the diameter of cerebral arterioles, their role in the regulation of brain blood flow in response to neuronal activity remains controversial.

Funding Notes

Self funded or sponsored students only - No University funding available at this time.

NB The University has some tuition fee scholarship - application deadline is 23 January 2019 at 5pm

How good is research at University of Sheffield in Psychology, Psychiatry and Neuroscience?

FTE Category A staff submitted: 34.45

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.

Your enquiry has been emailed successfully





FindAPhD. Copyright 2005-2018
All rights reserved.