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We have 17 Epidemiology (age) PhD Projects, Programmes & Scholarships

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Epidemiology (age) PhD Projects, Programmes & Scholarships

We have 17 Epidemiology (age) PhD Projects, Programmes & Scholarships

Early life factors in the development of Juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more

Metabolomic characterisation of adiposity across the life course

There is evidence that adiposity, measured by body mass index (BMI), causally influences a range of health outcomes, but little understanding of the mechanisms driving BMI effects. Read more

Modelling within-individual variability of clinical parameters and investigation of their effects on clinical decision-making

All measured clinical parameters vary within individual the same individual. This variation includes biological variation (chance variation around a physiological mean) and variation in the measurement process (measurement error). Read more

Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

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