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University of Oxford, Radcliffe Department of Medicine PhD Projects, Programs & Scholarships

We have 53 University of Oxford, Radcliffe Department of Medicine PhD Projects, Programs & Scholarships

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  Academic Endocrine Unit: investigating the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
  Prof R Thakker, Dr K Lines, Dr M Stevenson, Dr K Kooblall
Application Deadline: 26 July 2019
Other Potential Supervisors. Dr Asha Bayliss. The Academic Endocrine Unit investigates the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
  Aiming to elucidate the pathophysiological basis of human neurological disorders from genetic molecular networks to complex neural systems.
  Dr Z Cader
Application Deadline: 26 July 2019
Aiming to elucidate the pathophysiological basis of human neurological disorders from genetic molecular networks to complex neural systems.
  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
  Dr S Hyde, Dr D Gill
Application Deadline: 26 July 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
  B cell development and immune regulation: understanding B cell development and diseases associated with abnormal antibody production
  Prof R Cornall, Prof S Davis
Application Deadline: 26 July 2019
Our aims are to understand B cell development and diseases associated with abnormal antibody production. Inadequate or excessive immune responses lead to immunodeficiency or autoimmune and inflammatory diseases, which place a major economic and social burden on world health and the quality of human life.
  B Cell Immunology: studying the cellular interactions and molecular events that lead to the development of high affinity and protective antibodies during humoral immune responses
  Dr O Bannard
Application Deadline: 26 July 2019
We study the cellular interactions and molecular events that lead to the development of high affinity and protective antibodies during humoral immune responses.
  Cardiac energetics and integrative physiology: Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Prof C Lygate, Dr S Zervou
Application Deadline: 26 July 2019
Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 26 July 2019
It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Circadian control of energy metabolism and inflammation: Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology
  Prof D Ray
Application Deadline: 26 July 2019
Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology.
  Clinical Genetics: Building the skull – normal and abnormal development
  Prof A Wilkie, Dr S Twigg
Application Deadline: 26 July 2019
Working closely with the craniofacial teams based in Oxford and other UK units, we specialise in the application of whole exome and genome sequencing to children born with a serious malformation of the skull termed craniosynostosis.
  Clinical Genetics: De Novo Mutations, Selfish Selection, Mosaicism and Human Disease - developing methods for identification of new genes/molecular pathways subject to selfish selection within the human testis
  Prof A Goriely, Prof A Wilkie
Application Deadline: 26 July 2019
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
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