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University of Oxford, Radcliffe Department of Medicine PhD Projects, Programs & Scholarships

We have 30 University of Oxford, Radcliffe Department of Medicine PhD Projects, Programs & Scholarships

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Radcliffe Department of Medicine  University of Oxford

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I am a self funded student


We have 30 University of Oxford, Radcliffe Department of Medicine PhD Projects, Programs & Scholarships

Genomics and Genome Editing

My lab is interested in understanding how the genome functions and leveraging this to develop genome editing strategies to treat human disease. Read more

Recombination mechanisms in immunity and cancer

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.

Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more

Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells

Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more

Molecular dissection of blood cell fate determination

The Porcher lab investigates how Haematopoietic Stem Cells (HSCs, the cells with self-renewal and multilineage potentialities that give rise to the entire blood system) are produced during embryonic development. Read more

Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing

The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more

Modelling stem cell fate and alterations due to mutations

The group uses a combination of deep learning, stochastic models and Bayesian modelling to study questions relating to stem cell fate dynamics and how mutations in stem cells alter their normal behaviour, become fixed and accumulate in the tissue eventually leading to cancer. Read more

Single Cell Genomics

The Haematopoietic Stem Cell Biology (HSCB) Laboratory is focused on understanding how the normal haematopoietic stem/progenitor hierarchy is disrupted during the development of myeloid malignancies. Read more

De Novo Mutations and Human Disease

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis. Read more

Iron Biology

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism. Read more

Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development. Read more

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