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Biochemistry PhD Projects, Programs & Scholarships in Reading

We have 41 Biochemistry PhD Projects, Programs & Scholarships in Reading

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Showing 1 to 30 of 41
  SCENARIO - Soil microbial carbon metabolism for climate positive soils
  Dr E J Shaw, Dr M Redmile-Gordon, Dr R Griffiths
Application Deadline: 24 January 2020

Funding Type

PhD Type

Soils are essential to human well-being because they perform multiple functions that underpin the provision of ecosystem services that sustain life and regulate climate.
  The impact of gut microbiome and diet interplay on neurodegeneration
  Dr E Kevei
Applications accepted all year round

Funding Type

PhD Type

"Neurodegenerative disorders such as Parkinson’s, Alzheimer’s or Huntington’s disease represent major health risks and economic burden for the society.
  Protein engineering enzymes for Industry
  Prof K A Watson
Applications accepted all year round

Funding Type

PhD Type

We are interested in key features of protein sequence - structure - function relationship, and how this information can be translated to health.
  Bioinformatics studies of protein structures, functions and their interactions
  Dr L J McGuffin
Applications accepted all year round

Funding Type

PhD Type

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease.
  Biological role of Stress Hormones
  Dr A B Bicknell
Applications accepted all year round

Funding Type

PhD Type

OVERVIEW. Our lab focuses on the biological roles of peptide hormones derived from pro-opiomelanocortin (POMC), a protein produced in the anterior pituitary gland.
  British mosquito ecology: investigating the role of ecological traits, invasion status, and environmental factors in determining the distribution and seasonality of insect vectors in the UK
  Prof A Callaghan
Applications accepted all year round

Funding Type

PhD Type

Mosquito-borne diseases cause substantial mortality and morbidity worldwide and are changing in distribution and impact due to globalisation and environmental change.
  Cardiotoxicity of cancer drugs targeting the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade
  Prof A Clerk
Applications accepted all year round

Funding Type

PhD Type

"Heart failure is a leading cause of morbidity and mortality worldwide. The contractile cells of the heart, cardiomyocytes, possess many protective mechanisms, allowing them to withstand pathophysiological stresses.
  Gene and Cell Therapy For Muscular Dystrophy, Muscular Atrophy, Diabetes and Metabolic conditions
  Dr K Foster
Applications accepted all year round

Funding Type

PhD Type

Skeletal muscle development is a complex process and a number of regulatory factors for the different steps involved in stem cell activation and proliferation through to multinucleated, post-mitotic cells have been identified.
  Low density lipoprotein oxidation and atherosclerosis
  Prof D S Leake
Applications accepted all year round

Funding Type

PhD Type

"The research in Professor David Leake’s group is concerned with atherosclerosis, the underlying cause of. coronary heart disease and strokes.
  Studying the mechanisms that cause heart failure
  Dr S Boateng
Applications accepted all year round

Funding Type

PhD Type

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack, and this presents a huge economic burden each year.
  The molecular mechanisms underpinning individual variation in platelet function and their effect on the progression and treatment of cardiovascular disease.
  Dr CI Jones
Applications accepted all year round

Funding Type

PhD Type

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD). Platelets respond to a range of agonists, which are released when blood vessels are damaged, by aggregating together to form thrombi.
  The regulation of platelet function - towards new strategies to prevent thrombosis
  Prof J M Gibbins
Applications accepted all year round

Funding Type

PhD Type

Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding.
  Using CRISPR in iPS cells to modify platelet function
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

"Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus.
  Platelet-cell interactions: Platelets beyond thrombosis and haemostasis
  Dr A Pollitt
Applications accepted all year round

Funding Type

PhD Type

"Platelets play a key role in the prevention of bleeding following blood vessel damage.
  SCENARIO - Determining carbon pool turnover rates in semi-arid biomes of Australia as drivers of global carbon cycle inter-annual variability
  Dr K.H. White
Application Deadline: 24 January 2020

Funding Type

PhD Type

The atmospheric carbon component exhibits large interannual variability primarily driven by terrestrial processes, some of which are poorly understood.
  Field to Forest: Relict Field Systems in East Berkshire.
  Prof M Bell, Dr D Garrow
Applications accepted all year round

Funding Type

PhD Type

Flemming, 1987; Yates, 2007). The primary method for identifying these field systems has been aerial photography, which has identified extensive relict field systems on the Berkshire Downs (Ford, Bowden, Mees, & Gaffney, 1988; Levick, 2015; P.
  Understanding protein impact on soft wheat flour functionality: identification of protein markers for soft wheat breeding.
  Dr P Tosi, Prof D O'Sullivan
Applications accepted all year round

Funding Type

PhD Type

This is a fantastic opportunity to work at pre-breeding of soft wheat, specifically targeting its processing quality for the bakery sector.
  Understanding protein impact on soft wheat flour functionality: identification of protein markers for soft wheat breeding.
  Dr P Tosi, Prof D O'Sullivan
Applications accepted all year round

Funding Type

PhD Type

This is a fantastic opportunity to work at pre-breeding of soft wheat, specifically targeting its processing quality for the bakery sector.
  Maximising the efficacy of polyphenols on cardiovacular health
  Dr C Mills
Applications accepted all year round

Funding Type

PhD Type

"Cardiovascular diseases are the worlds’ leading cause of death. Dietary approaches to prevent or treat these diseases are becoming increasingly accepted.
  Silver ion-based antimicrobials: mechanisms of toxicity and resistance
  Dr G Mulley, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The emergence and persistence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of silver ions.
  Developing a virus-like particle (VLP) Polio vaccine
  Dr G Mulley
Applications accepted all year round

Funding Type

PhD Type

Rationale. Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the infectious disease Poliomyelitis (Polio).
  Molecular-genetic analysis of intra- and extra-cellular iron reduction systems in bacteria: role in gut colonisation and utilisation of dietary iron sources.
  Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

The innate immune defense systems respond to bacterial infection by reducing the amount of available iron in order to restrict bacterial growth.
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  Ubiquitin-dependent signalling pathways in ageing
  Dr E Kevei
Applications accepted all year round

Funding Type

PhD Type

Ageing is characterized by a general functional decline of cells with increased risk of disease. Maintenance of protein homeostasis is a long-term challenge not only for individual cells but also for the entire organism.
  Biological role of neuropeptides and their receptors
  Dr L Lander
Applications accepted all year round

Funding Type

PhD Type

"Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well.
  Systems level analysis of platelet signalling
  Dr M J Fry, Prof J M Gibbins
Applications accepted all year round

Funding Type

PhD Type

We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation.
  Multi-organ signalling and diseases. How maintaining skeletal muscle mass impacts the development of liver diseases
  Prof K Patel
Applications accepted all year round

Funding Type

PhD Type

Skeletal muscle has a number of roles in the human body beyond locomotion. It is has a vital role in controlling the metabolic activity the organism.
  The relationship between dietary iron and zinc, and the gut microbiota: Can dietary iron and zinc regime be exploited to improve health?
  Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The gut microbiota (100 trillion cells) outnumber human cells by 10 to 1. Its composition of around 500 to 1000 species is specific for each individual and is dynamic, changing with age, health and diet.
  The Gut Microbiota and Colorectal Surgery
  Dr M Lewis, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"Background. Antibiotic use prior to and following colorectal surgery is conventional practice, and is aimed at reducing the incidence of postoperative infection which is a major risk of such surgery.
  Biotechnological production microbial lipids rich in gamma-linolenic acid (GLA)
  Dr A Chatzifragkou, Dr D Charalampopoulos
Applications accepted all year round

Funding Type

PhD Type

Linolenic acid (GLA, ω-6 family) is a medicinally and nutritionally important polyunsaturated fatty acid (PUFA) with a broad spectrum of applications, extending from food supplements to anti-cancer formulations.
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