Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process. Read more
The gut microbiome has a profound effect on health and disease of humans and colorectal cancer (CRC) is one such disease influenced by microorganisms. Read more
Cancer is an evolutionary process. Cells in a tumour vary due to mutation, and so over many generations they adapt in response to both intrinsic selective pressures (such as anoxia) and extrinsic selective pressures (such as chemotherapy). Read more
Project Overview. . Saccharomyces cerevisiae is extensively used as model organism and is well understood from a sequencing perspective so up-regulation or down-regulation of gene expression is tractable. Read more
Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier. Read more
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