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Cell Biology / Development PhD Projects, Programs & Scholarships in Reading

We have 25 Cell Biology / Development PhD Projects, Programs & Scholarships in Reading

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  The impact of gut microbiome and diet interplay on neurodegeneration
  Dr E Kevei
Applications accepted all year round

Funding Type

PhD Type

"Neurodegenerative disorders such as Parkinson’s, Alzheimer’s or Huntington’s disease represent major health risks and economic burden for the society.
  Biological role of Stress Hormones
  Dr A B Bicknell
Applications accepted all year round

Funding Type

PhD Type

OVERVIEW. Our lab focuses on the biological roles of peptide hormones derived from pro-opiomelanocortin (POMC), a protein produced in the anterior pituitary gland.
  Cardiotoxicity of cancer drugs targeting the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade
  Prof A Clerk
Applications accepted all year round

Funding Type

PhD Type

"Heart failure is a leading cause of morbidity and mortality worldwide. The contractile cells of the heart, cardiomyocytes, possess many protective mechanisms, allowing them to withstand pathophysiological stresses.
  Impact of maternal obesity on offspring adipogenesis
  Dr D Sellayah
Applications accepted all year round

Funding Type

PhD Type

Obesity is the major health crisis of this generation. Thus, research into the mechanistic basis behind obesity is of paramount importance.
  Low density lipoprotein oxidation and atherosclerosis
  Prof D S Leake
Applications accepted all year round

Funding Type

PhD Type

"The research in Professor David Leake’s group is concerned with atherosclerosis, the underlying cause of. coronary heart disease and strokes.
  Studying the mechanisms that cause heart failure
  Dr S Boateng
Applications accepted all year round

Funding Type

PhD Type

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack, and this presents a huge economic burden each year.
  The molecular mechanisms underpinning individual variation in platelet function and their effect on the progression and treatment of cardiovascular disease.
  Dr CI Jones
Applications accepted all year round

Funding Type

PhD Type

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD). Platelets respond to a range of agonists, which are released when blood vessels are damaged, by aggregating together to form thrombi.
  The regulation of platelet function - towards new strategies to prevent thrombosis
  Prof J M Gibbins
Applications accepted all year round

Funding Type

PhD Type

Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding.
  Using CRISPR in iPS cells to modify platelet function
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

"Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus.
  Platelet-cell interactions: Platelets beyond thrombosis and haemostasis
  Dr A Pollitt
Applications accepted all year round

Funding Type

PhD Type

"Platelets play a key role in the prevention of bleeding following blood vessel damage.
  Maximising the efficacy of polyphenols on cardiovacular health
  Dr C Mills
Applications accepted all year round

Funding Type

PhD Type

"Cardiovascular diseases are the worlds’ leading cause of death. Dietary approaches to prevent or treat these diseases are becoming increasingly accepted.
  Biological role of neurooestrogens in behaviour
  Dr N Vasudevan
Applications accepted all year round

Funding Type

PhD Type

Our laboratory primarily investigates animal behaviour through the lens of neuroendocrinology i.e. hormones. We are interested in non-classical ways in which hormones may act to regulate behaviours.
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  Ubiquitin-dependent signalling pathways in ageing
  Dr E Kevei
Applications accepted all year round

Funding Type

PhD Type

Ageing is characterized by a general functional decline of cells with increased risk of disease. Maintenance of protein homeostasis is a long-term challenge not only for individual cells but also for the entire organism.
  Understanding the link between healthy ageing and social interaction
  Dr E Kevei, Dr N Vasudevan
Applications accepted all year round

Funding Type

PhD Type

Healthy ageing is a priority for all countries since we are living longer than ever before. A number of studies show that social behaviours can prevent some detrimental aspects of aging such as dementia and memory loss.
  Biological role of neuropeptides and their receptors
  Dr L Lander
Applications accepted all year round

Funding Type

PhD Type

"Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well.
  Systems level analysis of platelet signalling
  Dr M J Fry, Prof J M Gibbins
Applications accepted all year round

Funding Type

PhD Type

We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation.
  Multi-organ signalling and diseases. How maintaining skeletal muscle mass impacts the development of liver diseases
  Prof K Patel
Applications accepted all year round

Funding Type

PhD Type

Skeletal muscle has a number of roles in the human body beyond locomotion. It is has a vital role in controlling the metabolic activity the organism.
  Cell biology and evolution of cancer metastasis
  Prof P R Dash
Applications accepted all year round

Funding Type

PhD Type

We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers
  Dr F Greco, Prof H Osborn
Applications accepted all year round

Funding Type

PhD Type

Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier.
  Extracellular vesicles in health and disease
  Prof P Yaqoob, Dr D Tannetta
Applications accepted all year round

Funding Type

PhD Type

Endothelial dysfunction (ED) is associated with classical and emerging risk factors of cardiovascular disease (CVD), correlates with disease progression and is an independent predictor of the risk of future cardiovascular events.
  Functional Selectivity and the Regulation of Receptor-Activated Signaling Pathways
  Dr G Cottrell, Dr D Widera, Dr S Amadesi, Dr A McNeish
Applications accepted all year round

Funding Type

PhD Type

The molecular mechanisms that regulate receptors and receptor-activated signaling pathways in the cardiovascular and nervous systems are complex.
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
  Novel strategies for the diagnosis and treatment of snakebites
  Dr S Vaiyapuri
Applications accepted all year round

Funding Type

PhD Type

Snakebites represent a major neglected tropical disease affecting several million people worldwide and resulting in as many as 150000 deaths each year.
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