Skeletal muscle has a number of roles in the human body beyond locomotion. It has a vital role in controlling the metabolic activity the organism. Read more
Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more
Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression and impairment of memory. Read more
Project overview. The research in Professor David Leake’s group is concerned with atherosclerosis, the underlying cause of coronary heart disease and thrombotic strokes. Read more
Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more
Project Overview. Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding. Read more
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