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Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Reading

We have 8 Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Reading

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  Ion channel regulation in models of neurodegeneration
  Dr M Dallas, Prof G J Stephens, Dr A Bithell
Applications accepted all year round
Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated.
  Functional Selectivity and the Regulation of Receptor-Activated Signaling Pathways
  Dr G Cottrell, Dr D Widera, Dr S Amadesi, Dr A McNeish
Applications accepted all year round
The molecular mechanisms that regulate receptors and receptor-activated signaling pathways in the cardiovascular and nervous systems are complex.
  The effect of omega-3 polyunsaturated fatty acids (n-3 PUFA, “fish oils”), on vascular and potassium channel function
  Dr A McNeish, Dr G Cottrell, Dr F Tamagnini
Applications accepted all year round
There is a large body of evidence that consumption of oily fish or supplementation of fish oils leads to improvements in cardiovascular heath (as well as other health benefits including anti-inflammatory and anti-cancer effects).
  Novel strategies for the diagnosis and treatment of snakebites
  Dr S Vaiyapuri
Applications accepted all year round
Snakebites represent a major neglected tropical disease affecting several million people worldwide and resulting in as many as 150000 deaths each year.
  The molecular mechanisms underpinning individual variation in platelet function and their effect on the progression and treatment of cardiovascular disease.
  Dr CI Jones
Applications accepted all year round
Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD). Platelets respond to a range of agonists, which are released when blood vessels are damaged, by aggregating together to form thrombi.
  Using CRISPR in iPS cells to modify platelet function
  Dr C.E. Hughes
Applications accepted all year round
"Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus.
  Studying the mechanisms that cause heart failure
  Dr S Boateng
Applications accepted all year round
Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack, and this presents a huge economic burden each year.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
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