We have 20 University of Sheffield, School of Biosciences PhD Projects, Programmes & Scholarships

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School of Biosciences  University of Sheffield

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University of Sheffield, School of Biosciences PhD Projects, Programmes & Scholarships

We have 20 University of Sheffield, School of Biosciences PhD Projects, Programmes & Scholarships

Role of primary cilia in skeletal muscle stem cells and muscle regeneration

Primary cilia are cellular organelles present at the surface of many cell types in vertebrates. In recent years, they have been shown to play essential roles in relaying signalling information from the environment to the cell. Read more

The identification of allosteric inhibitors of high value therapeutic targets

This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more

PhD in land-based CO2 removal strategies for climate change mitigation

In a world facing the urgent challenge of climate change, it's clear that we need to take action. This PhD project aims to investigate land-based strategies for removing carbon dioxide (CO2) from the atmosphere. Read more

The analysis of HIF function in DNA repair and genome stability

DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more

Molecular characterisation of scavenger receptor ligand binding.

Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more

The regulation of scavenger receptors in cancer

The expression of some scavenger receptors has been identified as being poor for cancer prognosis. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously in the Human body. Read more

The genomics of rapid adaptation in grasses

We invite applications for a PhD in the area of genomics and rapid adaptation in plants. Our research combines cutting-edge genomic techniques, comparative analyses and experimental approaches to understand how organisms adapt to their environment. Read more

Cancer cells ‘feed’ on extracellular matrix components under starvation conditions: how can they do it?

Background. The tumour microenvironment (TME) has a key role in promoting tumour formation and progression. In breast and pancreatic cancers, this accompanied by the accumulation of extracellular matrix (ECM) in the TME. Read more

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

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