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University of Birmingham, School of Biosciences PhD Projects, Programmes & Scholarships

We have 17 University of Birmingham, School of Biosciences PhD Projects, Programmes & Scholarships

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School of Biosciences  University of Birmingham

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We have 17 University of Birmingham, School of Biosciences PhD Projects, Programmes & Scholarships

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Structure and function of Batten disease proteins

The neuronal ceroid lipofucscinoses are a group of inherited neurodegenerative disorders with primarily childhood onset. The most common form, also known as Batten disease or CLN3 disease, is caused by recessively inherited mutation in the CLN3 gene. Read more

Using novel ferronucleosides to study and regulate DNA replication in cells

Background. Replication of nucleic acid polymers like DNA is an essential process for all known forms of life. Furthermore, dysregulation and errors in DNA-replication are strongly linked with human diseases including cancer, as well as the process of cellular ageing. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

An interdisciplinary approach to tackling the problem of late Myeloma diagnosis.

There are two parallel studentships on offer. One (this project) is a wet lab project and the other is a bioinformatics project. Both are addressing the fact that multiple myeloma (MM) (a blood cancer of antibody producing cells) is nearly always diagnosed late. Read more

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