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University of Birmingham, School of Biosciences PhD Projects, Programs & Scholarships

We have 37 University of Birmingham, School of Biosciences PhD Projects, Programs & Scholarships

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  Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam
  Dr M Soller
Applications accepted all year round
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Biodiversity conservation ex situ or in situ with a focus on genetic diversity.
  Dr N Maxted
Applications accepted all year round
Field studies, ecogeography, geographic information systems and estimation of patterns of genetic diversity, IUCN taxonomic and genetic threat assessment will help elucidate conservation strategies and taxonomic clarity of critically endanged plant species.
  Differential ion mobility spectrometry and mass spectrometry for proteomics
  Prof H J Cooper
Applications accepted all year round
Research in our laboratory focuses on the application of state-of-the-art mass spectrometry techniques to the global analysis of peptides and proteins.
  Elucidating the mechanisms of phospholipid transport in Gram-negative bacteria
  Research Group: BBSRC MIBTP
  Dr T Knowles
Applications accepted all year round
This project focuses on characterising the fundamental process of outer membrane lipid transport in Gram-negative bacteria, a largely unknown process which is only now being revealed.
  Elucidating the pathobiology of Candida albicans
  Dr R Hall
Applications accepted all year round
The Hall lab is interested in understanding the biology and virulence factors of fungal pathogens. Our research largely focuses on the opportunistic fungal pathogen Candida albicans, which causes a range of infections from superficial mucosal infections (i.e.
  Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
  Dr M Soller, Prof F Mueller
Applications accepted all year round
Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017).
  Eukaryotic gene expression: understanding the role of UPF1 in global mRNA processing and amyotrophic lateral sclerosis (ALS)
  Dr S Brogna
Applications accepted all year round
This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  From start to finish: roles for the N-end rule pathway of protein degradation in plant development and stress-response
  Research Group: BBSRC MIBTP
  Dr D Gibbs
Applications accepted all year round
In order to effectively co-ordinate their growth and development, plants need to be able to respond to changes in their environment, whether it is adapting to the seasons or coping with stresses.
  Genetic and molecular mechanisms of brain structural plasticity and neurodegeneration
  Research Group: BBSRC MIBTP
  Dr A Hidalgo
Applications accepted all year round
The project will test the potential of a molecular mechanism that we recently discovered, in modulating brain structural plasticity versus neurodegeneration.
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