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The University of Manchester, Department of Chemistry PhD Projects, Programs & Scholarships

We have 26 The University of Manchester, Department of Chemistry PhD Projects, Programs & Scholarships

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  A bioinformatics approach to understanding protein solubility tags
  Dr J Warwicker, Dr R Curtis
Applications accepted all year round

Funding Type

PhD Type

The crowded environment of a cell cytoplasm reveals that proteins and other biological molecules co-exist at high macromolecular concentrations.
  A New Paradigm in “On Demand” Manufacture: Radiation Chemical Functionalisation During 3D Printing
  Dr A Baidak, Prof F Currell
Applications accepted all year round

Funding Type

PhD Type

The automation of modern economy has an immense impact on our everyday life; the development and implementation of machine learning and artificial intelligence will bring about further socio-economic changes of great significance and scale.
  A step change in the modelling of enzymatic catalysis
  Prof P Popelier, Dr L Johannissen
Applications accepted all year round

Funding Type

PhD Type

A deep understanding of enzymatic processes requires an atomic-level description, which is often beyond experimental techniques but achievable through synergy with computational chemistry.
  Accurate energy evaluation of receptor-ligand interaction
  Prof P Popelier, Dr S De Visser
Applications accepted all year round

Funding Type

PhD Type

Drug design routinely uses existing computational methods to evaluate the interaction energy between receptor (protein) and ligand (drug) in molecular docking.
  Assessing the Behaviour of Endotoxin in Biopharmaceutical Formulations: towards creating improved medicines
  Dr A Golovanov
Application Deadline: 15 November 2019

Funding Type

PhD Type

Supervisors. Dr Alexander Golovanov (The University of Manchester) and Dr Adrian Podmore (AstraZeneca). Biopharmaceuticals are the fastest-growing type of treatments for wide range of diseases, with enormous potential for personalised medicine.
  Characterising surface properties of protein biopharmaceutical molecules
  Dr A Golovanov, Dr J Warwicker
Applications accepted all year round

Funding Type

PhD Type

Protein biologicals have great potential for the effective treatment of a wide range of diseases. However, aggregation and instability are inherent issues with all protein pharmaceuticals, which is a problem that can limit their utility and developability.
  Control of antibiotic production through synthetic biology of bacterial hormone signalling
  Prof E Takano, Prof R Breitling
Applications accepted all year round

Funding Type

PhD Type

There is an urgent need for new antibiotics due to an increase in antibiotic resistance. To produce these essential drugs efficiently in biotechnological systems, we need to have a better understanding of the regulatory mechanisms of antibiotic production.
  Design, Synthesis and Biological Evaluation of novel inhibitors of the JAK-STAT signalling pathway with potential application as immune oncology agents
  Dr R Whitehead, Dr K Finegan, Prof N Turner
Applications accepted all year round

Funding Type

PhD Type

Small molecule inhibitors of the JAK-STAT signalling pathway often possess interesting biological properties with many displaying potent anti-proliferative activity towards cancer cell lines.
  Engineering synthetic ribosomal RNAs (rRNAs) in yeast
  Prof P Cai, Prof D Delneri
Applications accepted all year round

Funding Type

PhD Type

Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics.
  Engineering tRNA neochromosomes in yeast
  Prof P Cai, Prof D Delneri
Applications accepted all year round

Funding Type

PhD Type

Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics.
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