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University of Birmingham, School of Dentistry PhD Projects, Programs & Scholarships

We have 16 University of Birmingham, School of Dentistry PhD Projects, Programs & Scholarships

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  A potential role for Epithelial Mesenchymal Trans differentiation (EMT) in the Pathogenesis of Periodontal Disease
  Prof PR Cooper, Dr M Milward
Applications accepted all year round
Periodontitis is a ubiquitous chronic inflammatory disease that destroys the supporting structures of teeth; the most common form is chronic periodontitis which if untreated results in the breakdown of soft tissues and bone, ultimately leading to tooth loss.
  Analyses of large dental datasets using regression, structural equation modelling
  Prof T Dietrich, Mr P Sharma
Applications accepted all year round
A successful candidate will be supported in statistical analyses of large dental datasets. Analyses are likely to include. 1) Cross sectional data analyses using regression and structural equation modelling.
  Antibiotic Photo Disinfection for Oral health
  Prof PR Cooper, Dr M Milward
Applications accepted all year round
Oral diseases are the fourth most expensive diseases to treat globally (WHO, 2005), so developing new therapeutic management strategies to address these unmet needs in our population offers considerable public health benefit as well as potential for new product development.
  Cellular responses to radiation curing of resin-composite materials
  Dr R M Shelton, Prof W Palin, Dr P Cooper
Applications accepted all year round
Ultraviolet and visible light energy is routinely used for crosslinking a multitude of biomaterial applications ranging from hydrogels for tissue engineering and drug delivery, laser activated surgical adhesives to resin-based composite dental restoratives.
  Developing a three-dimensional research model of neutrophil-mediated tissue destruction during inflammation
  Dr J Hirschfeld, Prof I L C Chapple, Dr M Grant
Applications accepted all year round
Background. The proposed research has the goal to develop a novel 3D model to measure and visualise tissue destruction mediated by migrating neutrophils in vitro.
  Developing novel bioactive restorative materials
  Dr J Camilleri, Dr M Milward, Prof PR Cooper
Applications accepted all year round
This work will focus on gingival recession and the use of smart dental material in order to mitigate it. Gingival recession is prevalent in the adult population with studies suggesting that approximately 50% of the population has one or more recession defects this increases to 88% in over 65 year olds.
  Establishing a Scientific-Evidence Base for a Paradigm Shift for Regenerative Clinical Dentistry
  Dr J Camilleri
Applications accepted all year round
Management of diseases to the dental pulp is undertaken clinically using protocols that are historical and have no scientific background.
  Hydrogels for tissue engineering scaffolds containing cells
  Dr R M Shelton
Applications accepted all year round
The aim of the project is to investigate the potential of various polysaccharide hydrogels for use as tissue engineering scaffold materials to enable cells to be cultured both on and within the material.
  Intelligent algorithms for histological imaging
  Prof G Landini
Applications accepted all year round
This project is focused on the development of new computational approaches to resolve some fundamental problems related to the extraction of quantifiable information from microscopy images.
  Investigation into the potential of using different delivery systems of cultured oral keratinocytes as a possible treatment for mucosal defects
  Prof PR Cooper, Dr R M Shelton
Applications accepted all year round
The overall aim of the project is to investigate the possibility of being able to remove a small biopsy of a patients oral mucosa from a suitable site, expand the numbers of keratinocytes in culture, before seeding these cells onto a suitable delivery system and reimplanting into the patient over their mucosal defect.
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