We have 110 University of Dundee, School of Life Sciences PhD Projects, Programmes & Scholarships
University of Dundee, School of Life Sciences PhD Projects, Programmes & Scholarships
We have 110 University of Dundee, School of Life Sciences PhD Projects, Programmes & Scholarships
MSc by Research: Functional mechanisms and inhibition of biomedically important calcium channels
Ion channels are key components in every cell, bridging cell and organellar membranes for the traversal of charged species. Calcium channels are of particular physiological importance because of the central role calcium plays in cell signalling and cell death. Read more
MSc by Research: DNA Replication Coupled Mechanisms that control cell fate transitions
DNA replication is required for successful cell fate transitions across diverse physiological, experimental, and pathological contexts, involving factors often deregulated in human cancer and intellectual disabilities. Read more
MSc by Research: Cell migration in epithelial tissues
It is an important question to answer how cells move in a crowded environment. . In this project, we’ll use the vertex model (a widely used computational framework for cell-based studies of epithelial tissue mechanics) to study motion of a small patch of motile cells in otherwise inert environment. . Read more
MSc by Research: Immunomodulation by secreted proteins of helminth parasites
Parasitic helminths (worms) are master manipulators of the immune system. they secrete multiple proteins which interact with cells and cytokines of the immune response, inhibiting or skewing the response towards an outcome more favourable to them. Read more
MSc by Research: Optimizing plant cell wall glycan extraction to support plant health and biotechnology research
Plant cell wall glycans are a major component of plant biomass, essential for plant physiology, development, and protection against environmental stress and disease. Read more
MSc by Research: Understanding the contribution of natural variation in upstream open reading frames to plant climate adaptation
In our warming climate, understanding how plants respond to elevated temperatures is vital for breeding temperature-resilient crops. Read more
MSc by Research: Sugar ubiquitylation, a new quality control mechanism for the recognition and elimination of unbranched glycogen?
The accumulation and precipitation of unbranched glycogen in human tissues as toxic polyglucosan bodies (PB) underlies four human diseases that cause cardiomyopathy and heart failure and/or fatal neurological disorders. Read more
MSc by Research: Designing Molecular Glue Stabilizers to Restore Tumour Suppressor Function
Molecular glues, small molecules that facilitate the assembly of biomolecular complexes, have emerged as a transformative drug discovery strategy for treating diseases such as cancer and neurodegeneration. Read more
MSc by Research: Defying Mendel’s laws: developing tools to understand the principles of epigenetic inheritance in tomato plants
In plants, phenotypic innovation is not exclusively encoded in DNA sequences. Some heritable new traits are associated with modifications on the DNA, such as DNA methylation. Read more
MSc by Research: Conserved function of gut microbiome in mouse, fruit fly and Caenorhabditis elegans
Gut microbiome is the community of microbes living together in the gastrointestinal tract of an animal. They provide specific functions to the animal host such as digestion of cellulose and protection from invading pathogens. Read more
MSc by Research: Systems-level approaches to understanding mechanisms of cellular senescence and aging
Age-associated physiological decline is characterized by loss of resilience towards stress and injury. Understanding mechanisms of resilience is a global challenge due to the demographic shift towards aging populations. Read more
MSc by Research: Regulation of Kinetochore function by PLK1
Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy and it is a hallmark of cancer, while in oocytes represents the major source of miscarriages and genetic disease. Read more
MSc by Research: Unravelling the molecular mechanism underpinning Ubiquitin-like fusion protein proteolysis
The Maniaci Lab tackles one of the big puzzles in cell biology. How can cells create a vast diversity of proteins from a limited genetic blueprint? This diversity is essential for life and is largely achieved through post-translational modifications (PTMs) – molecular “tags” added to proteins after they’re made. Read more
MSc by Research: Bacillus subtilis biofilm formation and environmental stress
Biofilms have a significant impact in many environments including medical and agricultural sectors. Bacillus subtilis is a Gram-positive, spore-forming bacterium that is widely used as a model organism to increase our understanding of biofilm formation. . Read more
MSc by Research: Clustering the protein universe across the Tree of Life to enhance drug discovery
Drug discovery is the systematic process of identifying and optimizing molecular compounds to develop targeted medications for medical conditions. Read more