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We have 17 University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships

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School of Life Sciences  University of Nottingham

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University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships

We have 17 University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships

Psychedelic drugs and serotonergic modulation of functional connectivity in neuronal microcircuits

Psychoactive drugs result in profound alterations of our state of consciousness. Well known examples of such drugs are general anaesthetics, in use since mid-19th century, and psychedelics, which are consumed by different societies from times immemorial. Read more

The role of calcium signalling in regulating of tumour cell behaviour

Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more

How to build and maintain a 3-dimensional polarised epithelial sheet

We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more

Exosome biogenesis and organelle trafficking in neurodegeneration.

Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more

Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides

The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system. Read more

Functional characterization of gonococcal toxin-antitoxin systems

Toxin-antitoxin (TA) systems are commonly found in bacteria and comprise a stable toxin able to stall bacterial replication and an antitoxin that neutralises the activity of the toxin. Read more

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