We have 15 University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships
University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships
We have 15 University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships
Discovering blood-based biomarkers for improving clinical diagnosis of Dementia with Lewy bodies
Lewy body dementia (LBD) is the second most common cause of neurodegenerative dementia. Read more
Novel self-oxygenating and cell-instructive materials for chronic wound healing
Applications are invited for a fully funded 4-year PhD at the University of Nottingham in collaboration with Convatec Group Plc. The project aims at developing novel materials with unprecedented capability to engineer tissue microenvironment and heal diabetic wounds. Read more
Mitochondrial RNA metabolism in Lewy body dementia
Lewy body dementia (LBD) is the second most common cause of neurodegenerative dementia yet it is under-researched and underfunded. Read more
Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain
To apply, please contact Dr Graham Sheridan at Graham.Sheridan@nottingham.ac.uk. Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
Using genome engineering and bioinformatics to understand heterochromatin and centromere function in Schizosaccharomyces pombe and in cancer cells
Centromeres are the DNA sequences on eukaryotic chromosomes that mediate accurate chromosome segregation at both mitotic and meiotic cell divisions. Read more
The role of calcium signalling in regulating of tumour cell behaviour
Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more
The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease
Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more
How to build and maintain a 3-dimensional polarised epithelial sheet
We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more
The role of microtubule regulators in the progression of cancer: investigating the link between BRCA2 and depolymerising kinesins.
The mitotic kinesin KIF2C/MCAK regulates microtubule length in the mitotic spindle and plays a role in preventing chromosome-microtubule attachment errors. Read more
Providing insights into the molecular understanding of heart development and the formation of congenital heart defects.
Our research aim is to understand how the heart develops and then how it goes wrong to give rise to congenital heart defects (CHDs). Read more
Exosome biogenesis and organelle trafficking in neurodegeneration.
Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more
Saving the planet through carbon recycling: engineering bacterial capture of gasified waste for bioplastics production
Wider context. Climate change caused by the release of greenhouse gases from fossil fuels and through change of land use threatens life on our planet. Read more
Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides
The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system. Read more
Biology and genetics of reproduction in filamentous fungi
Fungi have beneficial but also detrimental properties. They are used for the production of foodstuffs and valuable pharmaceuticals and enzymes. Read more
Functional characterization of gonococcal toxin-antitoxin systems
Toxin-antitoxin (TA) systems are commonly found in bacteria and comprise a stable toxin able to stall bacterial replication and an antitoxin that neutralises the activity of the toxin. Read more
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