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We have 26 University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships

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University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships

We have 26 University of Nottingham, School of Life Sciences PhD Projects, Programmes & Scholarships

University of Nottingham

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Optimising novel pre- and rehabilitation strategies to improve the physiological resilience of older surgical patients

University of Nottingham School of Life Sciences
PhD Description. In addition to rehabilitation, which has long been employed as method to enhance recovery from clinical stress events, there is burgeoning clinical and research interest in prehabilitation, an approach employed to prepare individuals for these events. Read more
 Supervisor: Dr B Phillips
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Exploring the multi-organ benefits of Rapamune in relation to ageing physiology

University of Nottingham School of Life Sciences
PhD Description. Drug repurposing is an emerging avenue of research in the field of Geroscience; a field whose stated aim is to “accelerate research into the basic mechanisms driving ageing which could lead to improved clinical interventions”. Read more
 Supervisor: Prof P Atherton
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Exploring the role of habitual physical activity in driving physiological ageing

University of Nottingham School of Life Sciences
PhD Description. Robust evidence regarding the biological mechanisms responsible for the health benefits of physical activity, and the detrimental impacts of inactivity is lacking. Read more
 Supervisor: Prof P Greenhaff
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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BARIToNE: Using Next Generation Nitrogen Sources For Producing Spring Malting Barley and its Impact on Yield and Grain Malt Quality (Project code 24B)

University of Nottingham School of Life Sciences
Supervisors. Lead supervisor. Dr John Foulkes, University of Nottingham. Second supervisor. Dr Guillermina Mendiondo, University of Nottingham. Read more
 Supervisors: Dr M J Foulkes, Dr G Mendiondo, Mr S Smith
 31 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Psychedelic drugs and serotonergic modulation of functional connectivity in neuronal microcircuits

University of Nottingham School of Life Sciences
Psychoactive drugs result in profound alterations of our state of consciousness. Well known examples of such drugs are general anaesthetics, in use since mid-19th century, and psychedelics, which are consumed by different societies from times immemorial. Read more
 Supervisor: Dr MO Okun
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using genome engineering and bioinformatics to understand heterochromatin and centromere function in Schizosaccharomyces pombe and in cancer cells

University of Nottingham School of Life Sciences
Centromeres are the DNA sequences on eukaryotic chromosomes that mediate accurate chromosome segregation at both mitotic and meiotic cell divisions. Read more
 Supervisors: Dr W R A Brown, Dr W Wickstead
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of calcium signalling in regulating of tumour cell behaviour

University of Nottingham School of Life Sciences
Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more
 Supervisors: Dr M Georgiou, Dr IM Maiellaro
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The use of Drosophila melanogaster to identify novel therapeutic agents for Alzheimer’s disease

University of Nottingham School of Life Sciences
Since 2003, our understanding of the causes of Alzheimer’s disease (AD) have improved considerably, however, in that time only one new drug treatment has been approved. Read more
 Supervisors: Dr M Georgiou, Dr Z Zhu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How to build and maintain a 3-dimensional polarised epithelial sheet

University of Nottingham School of Life Sciences
We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more
 Supervisor: Dr M Georgiou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of microtubule regulators in the progression of cancer: investigating the link between BRCA2 and depolymerising kinesins.

University of Nottingham School of Life Sciences
The mitotic kinesin KIF2C/MCAK regulates microtubule length in the mitotic spindle and plays a role in preventing chromosome-microtubule attachment errors. Read more
 Supervisors: Dr C Friel, Dr S Wheatley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Competition and cooperation relationships within human microbial communities.

University of Nottingham School of Life Sciences
Typical studies of the human microbiome identify dysbiosis by sampling from healthy individuals, comparing them to individuals with a particular disease state, and reporting changes in the presence and/or abundance of bacterial species. Read more
 Supervisors: Dr F Whelan, Dr K Hardie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The Survivin Interactome in Health and Disease

University of Nottingham School of Life Sciences
Survivin is a small protein that is essential for life but that also contributes to disease, most notably cancer, in which its abnormal overexpression is linked to therapeutic resistance and metastasis. Read more
 Supervisor: Dr S Wheatley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain

University of Nottingham School of Life Sciences
Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
 Supervisor: Dr G Sheridan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Epigenomic transcriptomic mechanisms underlying human neuropsychiatric and neurodegenerative diseases

University of Nottingham School of Life Sciences
This project aims to use high throughput sequencing technologies and molecular approaches to understand how RNA epitranscriptomic processes contribute to susceptibility to human disorders of the brain. Read more
 Supervisor: Dr HM Knight
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A new approach to CRISPR-Cas adaptation and the discovery of host accessory-proteins

University of Nottingham School of Life Sciences
Bacteria provide many health benefits and eco-environmental services. Although physically simple, they have a sophisticated immune system, CRISPR-Cas. Read more
 Supervisors: Prof R Chalmers, Prof U Vinkemeier
 Year round applications  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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