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Queen’s University Belfast, School of Medicine, Dentistry & Biomedical Sciences PhD Projects, Programmes & Scholarships

We have 31 Queen’s University Belfast, School of Medicine, Dentistry & Biomedical Sciences PhD Projects, Programmes & Scholarships

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School of Medicine, Dentistry & Biomedical Sciences  Queen’s University Belfast

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We have 31 Queen’s University Belfast, School of Medicine, Dentistry & Biomedical Sciences PhD Projects, Programmes & Scholarships

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Structural, functional and molecular changes at the human peripheral retina

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
START DATE FOR PROJECT. 4 JANUARY 2023. The major aim of this study is to explore the relationship between structural, functional and molecular changes at the human peripheral retina using state of the art clinical imaging and functional testing, supplemented by molecule characterisation using cadaveric eyes. Read more

Three-dimensional structural mapping of the retinal neurovascular unit and the influence of diabetes

The aim of this PhD project is to better understand why people with diabetes are at risk of losing their vision. Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries. Read more

Using computational biology and transcriptional data to identify signaling that contributes to cancer progression

  Research Group: The Patrick G Johnston Centre for Cancer Research
Our group is looking to recruit a PhD candidate, with experience of working with molecular datasets, with an interest in performing translational bioinformatics analyses to understand the nuanced and complex interactions between cancer cells and their microenvironment for major emerging clinical tumour subtypes. . Read more

Using epigenetic modifiers in combination with 5-FU based chemotherapy to elicit tumour specific immune responses and immunogenic cell death in colorectal cancer.

HDAC inhibitors (HDACi) are an emergent class of epigenetic modifying agent (EMA), with multi-modal mechanisms-of-action in both tumour and tumour microenvironment (TME). This project aims to understand how these drugs modulate efficacy of 5-FU-based chemotherapy to counteract transcriptional plasticity and immune evasion that underpins emergence of treatment resistance. Read more

Targeting the ‘Worst of the Worst’ – developing novel treatments for Poor Outcome Triple Negative Breast Cancers.

We will investigate biology driving the aggressive features of Poor Outcome Triple Negative Breast Cancers (PO-TNBCs). PO-TNBCs possess the worst outcomes amongst all breast cancers, with high rates of metastases and chemoresistance. Read more

Local protein synthesis in angiogenesis

This proposal aims to investigate how localised mRNA translation within endothelial cells regulates blood vessel formation. Angiogenesis, or the emergence of new blood vessels, is a complex biological process that involves the coordinated migration of endothelial cells. Read more

Improving Oral Health in Care Homes

Poor oral health is a significant issue for older adults, particularly those living in nursing or residential care homes. Poor oral health impacts on quality of life, general health and nutrition. Read more

Identifying medications associated with cancer risk

In our previous research we systematically investigated 250 prescription medications to identify medications associated with cancer risk using a Scottish General Practice database. In this project we will attempt to replicate some of the findings from our screening study. Read more

Identifying immune mechanisms in the CNS as targets for the treatment of paediatric Multiple Sclerosis (MS)

Paediatric MS accounts for 2.7-10.5% of the total MS population and can affect children of all ages. Paediatric MS is not curable and as such, is a lifelong debilitating disease that restricts the life quality of affected children for their entire life. Read more

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