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Continue with FacebookWe have 24 University of Sheffield, School of Medicine and Population Health PhD Projects, Programmes & Scholarships
University of Sheffield, School of Medicine and Population Health PhD Projects, Programmes & Scholarships
We have 24 University of Sheffield, School of Medicine and Population Health PhD Projects, Programmes & Scholarships
Developing CCDC146 as a therapeutic target for Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease caused by the selective and progressive death of motor neurons. Read more
Multi-modal assessment of Parkinson’s Disease to investigate the relationship between mobility and mitochondrial dysfunction - S3.5-SMP-Buckley
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterised by loss of dopaminergic neurons in the basal ganglia of the brain. Read more
Improving the outcome of surgical treatment for liver cancer: combining advanced medical imaging and computational fluid dynamics for personalised treatment planning - S3.5-SMP-Sourbron
Why are we doing this project?. Liver resection is the only curative option for many patients with liver cancer, but it is often a difficult balancing act. Read more
Engineering an in vitro human embryo implantation platform to study pathologies arising in early pregnancy - S3.5-SMP-Lucas
Embryo implantation is the step in early pregnancy where the founding tissue of the placenta from the embryo, called the trophoblast, establishes a physical connection with the mother at the inner lining of the uterus, called the endometrium. Read more
A versatile tumour-on-a-chip platform for studying tumour cell metastasis and angiogenesis - S3.5-SMP-Bryant
Studying metastasis and angiogenesis is essential for developing effective cancer treatments. Metastasis, the process by which cancer cells spread from the primary tumour to other parts of the body, is responsible for the majority of cancer-related deaths. Read more
Single-molecule investigation of how flap-endonucleases recognise and cleave DNA structures to allow DNA replication - S3.5-SMP-Sayers
Replication of DNA is one of the most fundamental processes of life, and the molecular machinery required in this process are some of the most evolutionarily ancient and universally conserved. Read more
Developing the evidence base for the visual presentation of complex data to clinicians - S3.5-SMP-Alix
Innovations using complicated maths such as artificial intelligence promise much in health care, from better diagnosis to better treatment. Read more
Investigation of the biological behaviour and genetic regulation of rare cancers, to develop new therapies.
We are an active research group investigating ocular tumours, sarcomas, and have an interest in thyroid cancer. Currently we have five PhD students who are in various stages of their study. Read more
Ex vivo drug screening in paediatric cancer
Cure rates for many childhood blood cancers are high but remain poor in some solid tumours. Even in childhood solid cancers which are curable, the toxic drugs and radiotherapy used leave many survivors having life-long health problems. Read more
The effects of research culture on the diversity and career progression for female ethnic minority staff in academia across disciplines: a mixed-methods analysis and thematic framework
Project description. In order to conduct research that is sufficiently reflective of the entire population, research teams needs to be diverse and inclusive to reflect the full range of communities they are researching. Read more
Modulation of Smooth Muscle Cell Function by Neutrophil Microvesicles
The leading cause of death globally is cardiovascular disease (CVD), according to the World Health Organisation. Atherosclerosis is the underlying cause of most of these. Read more
The role of endothelial PKD1 in endothelial dysfunction and formation of aortic aneurysms
Polycytin-1 (PKD1) is the main causative gene for autosomal dominant polycystic kidney disease (ADPKD) affecting every 1 in 400 to 1,000 people. Read more
How well can mice reproduce human frailty?
We are living longer but not necessarily healthier. One condition that affect older people is frailty, which makes people vulnerable to stressors such as infections or falls in a much more profound way than younger people. Read more
Should I stay or should I go now? Programming immune cell retention versus resolution at sites of tissue damage
The white blood cells known as macrophages are fundamental for development, homeostasis and defences against infections and altered self. Read more
Old age macrophages? Programming distinct immune behaviours across the lifecourse
The white blood cells known as macrophages are a highly heterogeneous population of cells and this diversity is necessary for their plastic responses to a changing microenvironment and a wide-range of required functions in vivo. Read more
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