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Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships

We have 52 Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships

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School of Pharmacy  Queen’s University Belfast

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We have 52 Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships

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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Self-Navigating Nanocarriers for Intracellular Protein Delivery

Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more

Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery

Lipid nanocapsules (LNCs) are very interesting nanoformulations as they can be made by phase inversion technique (PIT), a scalable method with predictable particle size at the beginning of the preparation process. Read more

Production of super small nanocrystals for drug delivery to target tissues

The student will be involved in an exciting project related to the design, formulation and in vitro/in vivo characterisation of super small drug nanocrystals with specific surface properties to enhance drug accumulation in target tissues, such as the lymphatic or central nervous systems. Read more

Prescribing, medicine access and medicines use in community-based palliative care

Community medical and nursing teams are increasingly called upon to deliver palliative and end-of-life care to terminally ill people living in their own homes and in long-term care settings such as nursing homes. Patients and carers may experience problems in medicines access, and processes can be lengthy and burdensome. Read more

Peptide-based nanoparticles for brain targeted gene delivery

Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more

Novel poly(acrylic acid) complexes for enantioselective drug delivery and chiral separation

Poly(acrylic acid)s (PAA) are widely used as emulsifiers, suspending agents and viscosity enhancers within the pharmaceutical, cosmetic and food industries owing to their low cost and excellent safety profile when administered orally or applied topically. Read more

Multifunctional Biomaterials to Combat Infection and Modulate Inflammation

Implantable medical devices are commonplace in modern medicine (e.g. joint replacements, stents, artificial heart valves, etc.), and are of ever increasing interest in the field of regenerative medicine. Read more

Microfluidic technologies for the production of Nanomedicines

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge. Read more

Mechanochemical synthesis of polymer-drug conjugates via reactive extrusion

Polymer–drug conjugate (PDCs) therapeutics are pharmacologically active macromolecular constructs comprising at least one therapeutic agent covalently bound to a polymeric carrier. Read more

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