Continue with FacebookLooking to list your PhD opportunities? Log in here.
We have 47 Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 47 Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
PhD saved successfully
Countering the proteinase-activated receptor 1 (PAR-1) pro-tumour phenotype using a novel nanotherapeutic approach
Proteinase-activated receptor 1 (PAR1) is a G-protein coupled receptor (GPCR) expressed on a number of cell types, and is activated by serine proteases such as thrombin, plasmin and activated protein C. Read more
Combining protein modelling and synthetic biology to alter and expand of host range of phages
Phage therapy relies on the use of bacterial viruses for treatment of infectious diseases. Bacteriophages are natural predators of bacteria, but their specificity varies significantly depending on the host species. Read more
Cold Plasmas for Enhancement of Intracellular Delivery of Macromolecules
Cold plasmas are partially or completely ionised gases which are generated at or near ambient temperatures. Read more
Chemical glycoengineering of therapeutic antibodies
Glycosylation is the most common posttranslational protein modification. Recombinant therapeutic glycoproteins (RTGs) such as monoclonal antibodies (mAbs) are decorated with complex glycans that determine not only their efficacy but also other critical parameters such as in vivo half-life, stability and antigenicity. Read more
Bio-inspired liquid-like coatings for medical devices to combat biofilms and associated infections
Biofilms are microbial cells embedded within a self-secreted extracellular polymeric substance matrix, which are central to some of the most urgent global challenges across diverse fields of application, from medicine to industry and exert considerable economic and social impact. Read more
Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis
Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more
Antibiotic Resistance and Biofilm Formation in Clinical Isolates of Enterococcus faecium – a WHO High Priority Pathogen
E. faecium is an important human pathogen which exhibits resistance to a range of antibiotics, and is implicated in a wide variety of device associated infections. Read more
Advanced manufacturing of paediatric formulations with poorly water soluble drugs
This project employs an advanced manufacturing technique, microwave-induced in situ amorphization, in combination with a wide range of characterization techniques to tackle the consistent stability issue of amorphous solid dispersions as a means of improving the dissolution performance of paediatric personalised formulations with poorly water soluble drugs. . Read more
3D-Printing of implantable devices for the treatment of chronic conditions
Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more
3D printing of drug delivery implants
Additive manufacturing (AM) encompasses a wide range of processes that create structures through deposition or binding of materials in successive layers to produce a 3D object. Read more
3D & 4D printing in cancer management
According to WHO, cancer is the second leading cause of death worldwide, with nearly 1 in 6 deaths been due to cancer. The principal modes of cancer management are surgery, radiotherapy, chemotherapy and pharmaceutical agents. Read more
Dissecting mechanism of drug responses to novel anti-cancer therapies
Repurposing drug screens with compounds that have already gained FDA approval can accelerate the identification of new therapies to treat an illness and in the cancer setting extend life or provide compassionate care. Read more
Development and Machine Learning-based Drug Release Prediction of Age-appropriate Combined Therapy
This project is proposed to develop age-appropriate (geriatric/paediatric) combined therapy with poorly water soluble drug(s) using advanced manufacturing methods, i.e. Read more
Nanoparticle delivery of antibiotics for treatment of pulmonary infection
Antimicrobial resistance (AMR) poses a major global risk to human health by causing death, disability, longer hospitalisations, and increased healthcare costs. Read more
Characterising biofilms in endotracheal tubes to direct a new strategy for preventing ventilator-associated pneumonia in critically ill adults
Endotracheal tubes (ETTs) are employed for invasive mechanical ventilation of critically ill patients with acute respiratory failure. Read more