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We have 15 University of Reading, School of Pharmacy PhD Projects, Programmes & Scholarships
University of Reading, School of Pharmacy PhD Projects, Programmes & Scholarships
We have 15 University of Reading, School of Pharmacy PhD Projects, Programmes & Scholarships
DEVELOPMENT OF LIVE INVERTEBRATE MODELS FOR TOXICOLOGICAL AND ANTIMICROBIAL SCREENING OF BIOACTIVE MOLECULES, NANOMATERIALS AND DRUG DELIVERY SYSTEMS
Live invertebrates offer significant value for research into toxicology and drug delivery due to their simple yet highly relevant biological systems, which share many similarities with higher organisms. Read more
Molecular Mechanisms of Receptors in Inflammation and Pain
Are you interested in understanding how the cardiovascular and nervous systems work? Join our research team to study the molecular mechanisms that regulate receptors and their signaling pathways. Read more
Investigating Platelet and Megakaryocyte Signalling Using Advanced Microscopy Techniques
Investigating Platelet and Megakaryocyte Signalling Using Advanced Microscopy Techniques. Read more
Novel strategies for the diagnosis and treatment of snakebites
Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more
Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers
Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier. Read more
Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases
Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more
Developing novel formulations and materials for transmucosal drug delivery
Mucosal routes of drug administration offer numerous advantages including ease of application, non-invasive nature and sometimes possibility of targeting particular organs. Read more
Development of lung in vitro model to assess antimicrobial activity
When developing new inhaled antibiotics to treat lung infections, they will need to be tested before being given to humans. Current methods to test inhaled antibiotics are based on animals which are both inhumane and lack efficacy. Read more
Advanced crystal structure determination methods for pharmaceutical powders
A knowledge of the crystal structures of molecules of pharmaceutical relevance is extremely important in understanding their physical, chemical and biological properties. Read more
Understanding the biological role of the i-motif
The DNA i-motif is an important biological target which has recently been shown to form inside the nucleus of human cells. Current understanding of this structure is limited as it has received little research focus over the last 30 years, primarily because it was thought it couldn’t exist within biological environment. Read more
Biological role of neuropeptides and their receptors
Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more
Resilient dementia medication management in the home
Dementia medication management is a broad area. This project will focus specifically on medication management within people’s own homes, applying a Resilient Healthcare approach. Read more
Formulation of poorly-soluble drugs
Poorly water-soluble drugs is an important class of pharmaceutical compounds that are finding numerous applications for the therapy of different pathological conditions. Read more
Ion channel regulation in models of neurodegeneration
Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated. Read more
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