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We have 40 Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships for Self-funded Students

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School of Pharmacy  Queen’s University Belfast

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Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships for Self-funded Students

We have 40 Queen’s University Belfast, School of Pharmacy PhD Projects, Programmes & Scholarships for Self-funded Students

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more

Synthetic Protein-Transporters for Enhanced Transduction Activity

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Selective targeting of furin for the treatment of fibrotic lung disease.

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Developing biodegradable long acting drug delivery systems for the treatment of chronic conditions

Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more

Peptide-based nanoparticles for brain targeted gene delivery.

Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more

Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

One in two people will develop cancer in their lifetime and it is a leading cause of death.  While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. . Read more

Self-regulating, self-cleaning biomaterials

A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

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