Globally, nearly 189,000 people die each year as a result of brain cancer and around 250,000 people are diagnosed with a malignant brain tumour (umbrella name. Read more
Some brain cancers cannot be surgically removed, and many potent therapeutics cannot reach the tumour site. This project aims to overcome these hurdles by utilizing a recently developed multifunctional nanoparticle drug delivery system that can be injected directly into tumours. Read more
Glioblastoma multiforme (GBM) is the most common primary brain tumour, with a dismal median survival. The tumour microenvironment (TME) is the microscopic-scale environment of tissue in which a tumour evolves and is a key component that controls GBM aggressiveness. Read more
Glioblastoma (GBM) is the most aggressive and lethal primary brain tumour in adults, with a high recurrence rate and limited treatment options. Read more
Over the past four decades, significant advancements have been made in the treatment of childhood cancer, leading to a substantial increase in cure and survival rates. Read more
Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more
To apply, please contact Dr Graham Sheridan at Graham.Sheridan@nottingham.ac.uk. Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
Background. High-grade gliomas are the most common cancers arising within the brain and contribute to ~190,000 brain tumour related deaths/year globally. Read more
Medulloblastoma is the most common paediatric malignant brain tumour, accounting for 20% of childhood brain tumours cases per annum in the United Kingdom alone, with approximately one-third of patients dying from the disease worldwide. Read more
The invasive behaviour of glioblastomas (the commonest, most malignant primary brain tumour) means that local treatments won’t cure these tumours, and this diffuse invasion means that there is a disruption of normal cognitive structures. Read more
By 2050 the number of people living with neurodegenerative disorders are set to double. Alzheimer’s disease in particular is set to become a public health emergency. Read more
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