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We have 25 drug metabolism PhD Projects, Programmes & Scholarships for Self-funded Students

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drug metabolism PhD Projects, Programmes & Scholarships for Self-funded Students

We have 25 drug metabolism PhD Projects, Programmes & Scholarships for Self-funded Students

Quantitative prediction of drug metabolism mechanism

Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology . The project aim is the high-accuracy prediction of drug metabolism mechanism with the help of atomistic simulations at quantum accuracy and machine learning. Read more

Drug metabolism - prediction, detection, and isolation

Electrosynthesis (ES) is a green methodology for preparing and interpreting drug metabolites linked to toxicology. ES describes the synthesis of chemical compounds in an electrochemical cell. Read more

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Development of antibody-drug conjugates (ADCs) for oncology indications

  Research Group: Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Evaluation of prognostic markers and drug targets for management of patients with adrenocortical carcinoma (ACC)

We are seeking talented, motivated students with a passion for research in adrenal tumours led by Dr. Cristina L Ronchi (web https://www.birmingham.ac.uk/staff/profiles/metabolism-systems/ronchi-cristina.aspx). Read more

The role of GLUT transporters in microglial metabolism, investigating functionality, regulation and drug targetable properties.

Modifying the brain’s metabolism as an intervention or for the treatment of Alzheimer’s disease represents a novel strategy for targeting what is recognised as a multifactorial condition which lacks effective therapeutic options.   . Read more

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Microfluidic Encapsulation of biologics into Nanomedicines

Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more

Faculty of Pharmacy, Masaryk University

Discover the art of developing life-changing pharmaceuticals through our Medicinal Chemistry program. The aim of this programme is to prepare qualified experts who will work professionally in scientific activities in the field of development and analysis of drugs and its application to other scientific fields. Read more

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