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embryonic development PhD Projects, Programmes & Scholarships
We have 20 embryonic development PhD Projects, Programmes & Scholarships
We have 20 embryonic development PhD Projects, Programmes & Scholarships
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MSc by Research: Understanding the beginning of life: the role of non-canonical ubiquitylation in early embryonic development
Ubiquitin is a small, yet influential, protein that is attached to other substrates to control their stability or activity in a process called ubiquitylation. Read more
MSc by Research: Does CDK1 regulate NICD turnover in a cell cycle dependant manner in Drosophila Melanogaster?
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life, including cell fate specification within progenitors. Read more
Dissecting the role of novel haematopoietic factors in development and disease
Blood is made up of different cell types with different functions, such as carrying oxygen (red blood cells), help with wound healing (platelets) and fighting infections (white blood cells). Read more
Defining the role of WT1 in cellular and molecular processes during gastrulation, in embryos and gastruloids
In an ageing population, injury and degenerative processes lead to increased pressure on the NHS due to demand on treatments. Read more
Identifying novel regulators of haematopoiesis using flies
Supervisors. Iwan Evans (primary supervisor); Steve Brown (Biosciences, secondary supervisor). Project details. Control of blood cell proliferation, survival and activation is critical to the health of an organism. Read more
Meals for macrophages – investigating how macrophages engulf and process dying cells in vivo
Supervisors. Iwan Evans (primary supervisor); Phil Elks and Simon Johnston (secondary supervisors). Project details. A critical role for phagocytic cells such as macrophages is the engulfment and subsequent degradation of dying cells and debris. Read more
Investigating the control and function of macrophage subtypes using Drosophila melanogaster
Supervisor(s). Iwan Evans (Primary Supervisor, IICD) and Martin Zeidler (Second Supervisor, Biosciences). Project details. The phagocytic white blood cells known as macrophages are a highly heterogeneous population of cells. Read more
MSc by Research: Regulation of the stability of the Notch intracellular domain in iPS derived presomitic mesoderm cells
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life. Read more
Modelling scar formation in endometriosis
This opportunity will remain open until the position has been filled and so early applications are encouraged. Endometriosis affects 10-15% of women during their reproductive years and is often associated with debilitating pelvic pain and impaired fertility. Read more
Ion channel signalling in cancer cells
Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more
Mechanisms of primary cilia formation
Affiliation. Masaryk University, Faculty of Medicine. Study program. Ph.D. program Biomedical Sciences. Specialization. Biochemistry and Molecular Biology. Read more
Stochastic modelling and inference for live-cell gene expression data to unravel the mechanisms of stem cell differentiation
Research Group:
Statistical Medicine and Molecular Biology
This project will develop statistical methodology and computational algorithms to estimate model parameters using live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more
Mechanisms of primary cilia formation
The primary cilium is an enigmatic, antenna-like organelle present on the surface of most cells. Whilst it was originally described as a vestigial organelle, recent years have indisputably proven its status as a seminal structure for sensing various extracellular stimuli. Read more
Characterising novel regulation processes for a structurally important skeletal gene
Cartilage is a specialised tissue, which performs essential roles in the functioning skeletal. Read more
ABM CDT Comparison of pluripotent and multipotent stem cells in articular cartilage bioprinting
Articular cartilage (AC) defects are one of the major causes of immobility and poor quality of life for millions of individuals worldwide, but current medical therapies fail to provide long-term restoration of pain-free function. Read more
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