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We have 84 enzymes PhD Projects, Programmes & Scholarships for Self-funded Students

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enzymes PhD Projects, Programmes & Scholarships for Self-funded Students

We have 84 enzymes PhD Projects, Programmes & Scholarships for Self-funded Students

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine
The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more
 Supervisors: Dr A Saurin, Dr T Ly
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Building Enzymes with New Catalytic Functions & Design and Evolution of Enzymes with New Catalytic Functions

The University of Manchester Department of Chemistry
A fully funded studentship is available, based at the Manchester Institute of Biotechnology under the supervision of Prof Anthony Green. Read more
 Supervisor: Prof A Green
 31 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health
We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more
 Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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A reactive fragment approach to dissect the zDHHC enzymes

University of Strathclyde Department of Pure and Applied Chemistry
Key Words: Synthetic Chemistry; Chemical Biology; Drug Discovery; Medicinal Chemistry; Organic Synthesis; Organic Chemistry. Read more
 Supervisors: Prof N Tomkinson, Prof L Chamberlain
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Identification, characterisation and novel expression of plastic-degrading enzymes in bacterial spores

Anglia Ruskin University ARU School of Life Sciences
Fixed term contract for 3 years, commencing September 2024. Bursary of £19,237 per annum and a full fee-waiver for UK tuition fees. Read more
 Supervisor: Dr H McRobie
 31 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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The role of ubiquitin-modifying enzymes in angiogenesis

University of Leeds Faculty of Biological Sciences
The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Dr S Ponnambalam, Dr M A Harrison
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisors: Prof D Panne, Dr T Schalch
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Novel glycoprotease discovery and characterisation for enhanced detergent performance

Newcastle University BiSCoP CTP
In this exciting joint academia-industry project the student will exploit metagenomes and the huge untapped capacity of the human gut microbiota to breakdown glycoconjugates to discover novel protease enzymes that can potentially increase the performance and environmental sustainability of leading P&G automatic dishwashing brands. Read more
 Supervisors: Dr E Lowe, Dr D Bolam, Dr AL Morales Garcia, Mrs K Bell-Rusiewicz
 2 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisor: Prof D Panne
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design and Evolution of Enzymes with New Catalytic Functions

The University of Manchester Department of Chemistry
A fully funded studentship is available, based at the Manchester Institute of Biotechnology under the supervision of Prof Anthony Green. Read more
 Supervisor: Prof A Green
 31 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Discovery of enzymes for plastic degradation

University of Nottingham School of Chemistry
Dr Luisa Ciano, Dr Anca Pordea and Dr Sam Bryan. Application deadline. open until filled, applications reviewed on a weekly basis. Read more
 Supervisors: Dr L Ciano, Dr A Pordea, Dr S Bryan
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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MSc By Research: Matching genotype and phenotype: Comparing genome sequences of multiple gut anaerobic bacteria to identify key substrate degrading enzymes

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Prof K Scott, Dr I Mukhopadhya, Dr L Van de Lagemaat
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The identification of allosteric inhibitors of high value therapeutic targets

University of Sheffield School of Biosciences
This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more
 Supervisor: Prof J P Waltho
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel targeted therapeutic approaches through induced-proximity of proteins

University of Dundee School of Life Sciences
Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more
 Supervisors: Prof G Sapkota, Prof A Ciulli
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy
Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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