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We have 59 gene regulation PhD Projects, Programmes & Scholarships for Self-funded Students

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gene regulation PhD Projects, Programmes & Scholarships for Self-funded Students

We have 59 gene regulation PhD Projects, Programmes & Scholarships for Self-funded Students

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Gene regulation in cancer metastasis

King’s College London Randall Centre for Cell and Molecular Biophysics
A PhD project studying gene regulation in cancer metastasis is available in the laboratory of Dr. Fiona Wardle (https://www.kcl.ac.uk/research/wardle-group) in the Randall Centre for Cell and Molecular Biophysics, King’s College London. Read more
 Supervisors: Dr F Wardle, Prof C Wells
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more
 Supervisor: Dr J Min
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy
Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more
 Supervisor: Dr G S Winkler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll, Dr GL Leyden
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Understanding gene regulation by HDAC1 complexes in development and cancer

University of Leicester Molecular and Cell Biology
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
 Supervisor: Prof S Cowley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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mRNA epigenetics: Charaterization of a novel layer of gene regulation for essential brain functions

University of Birmingham School of Biosciences
For over 40 years we know about modified nucleotides in mRNA, but the functions for these essential modifications are largely elusive. Read more
 Supervisor: Dr M Soller
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The University of Manchester Faculty of Biology, Medicine and Health
The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more
 Supervisors: Dr M Lagator, Prof M Rattray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisors: Prof D Panne, Dr T Schalch
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisor: Prof D Panne
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Human Genetics, Genomics and Disease: Sequence determinants of mRNA fate in neuronal differentiation

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center Berlin Institute for Medical Systems Biology, Berlin, Germany. Read more
 Supervisor: Dr G Kudla
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating the role and regulation of membraneless granules for the development of T. brucei

University of York York Biomedical Research Institute
Adaptation to a change of environment is an essential process for survival, in particular for parasitic organisms exposed to a wide range of hosts. Read more
 Supervisors: Dr M Cayla, Dr P B Walrad
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self funded MSc by research or PhD in Biology: Membraneless biomelecular condensates, a major regulator of trypanosome parasites differentiation and host adaptation

University of York Department of Biology
Lead supervisor: Dr Mathieu Cayla. Co-Supervisor. Dr Pegine Walrad. The student will be registered with the Department of Biology. Read more
 Supervisor: Dr M Cayla
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more
 Supervisor: Dr NB Benabdallah
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology
The 46th chromosome in XX female mammals, the second X, has to be switched off. That way females equalize gene dosage of X-linked genes with XY males. Read more
 Supervisors: Dr Y Markaki, Prof J Schwabe, Dr JH Hodgkinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences
Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more
 Supervisors: Dr HL Wright, Prof MJ Peffers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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