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genetic manipulation PhD Projects, Programs & Scholarships

We have 49 genetic manipulation PhD Projects, Programs & Scholarships

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We have 49 genetic manipulation PhD Projects, Programs & Scholarships

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Uncovering the molecular basis of cellular memory in plants

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details. Read more

Tumour metabolic and immune landscape in spatial resolution: using engineered bacterial cancer therapy to enhance anti-tumour T cell responses

Bacterial cancer therapy (BCT) is a promising and versatile therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is the most well-studied among bacterial vectors due to advantages in ease of genetic modification, metabolic adaptation, and motility. Read more

BBSRC White Rose DTP Studentship - Understanding the role of intracellular trafficking in in vivo cell polarisation during tissue patterning using state-of-the-art imaging and gene manipulation tools

Cell polarity is a fundamental cellular property that determines the form and function of the organs and tissues in our bodies. While well-studied in single cells, a major frontier in cell and developmental biology is to understand how cell polarity can be established and coordinated within a tissue. Read more

Precision Medicine DTP – Why don’t spinal cord OPCs remyelinate well in multiple sclerosis and how do we fix it?

  Research Group: MRC Centre for Regenerative Medicine
Additional supervisor. Associate Prof Gonçalo Castelo Branco [Karolinska Institute]. Background. Oligodendrocytes are the myelin-forming cells of the central nervous system (CNS), providing both insulation to enhance nerve conduction velocity and metabolic support for the underlying axon. Read more

Finding new antibiotics in the soil microbiota (MALONE_J22MMB)

The increase in drug-resistant bacterial infections is a major global health threat. This crisis is exacerbated by a lack of new antibiotics, caused by multiple factors including the frequent rediscovery of known antibiotics. Read more

Genome mining of novel antimicrobial and antiviral natural products from new bacterial strains

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Transcriptional control of vascular development

Sprouting of new capillaries from pre-existing vessels (angiogenesis) promotes the formation of almost all blood vessels during development, growth and tissue regeneration. Read more

Elucidating and exploiting molecular mechanisms of bacterial natural product biosynthesis

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details. Read more

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