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genomic PhD Projects, Programmes & Scholarships
We have 112 genomic PhD Projects, Programmes & Scholarships
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Comparative genomics of insects and their microbiomes to explain feeding ecology dynamics
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention
The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more
Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention
The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more
Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
Research Group:
BBSRC MIBTP
Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017). Read more
The Mechanisms of Epigenetic Regulation in Ageing and Age-Related Neurodegeneration
We are seeking a bright, talented, and highly motivated PhD student to lead a project investigating basic mechanisms of epigenetic regulation and their involvement in ageing and age-related neurodegeneration. Read more
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Single-cell analysis of stress memory in plants
Plants are sessile organisms that are known for their adaptive plasticity to the changing environment. Environmental changes cannot only influence gene expression patterns but also affect the stability of the genome. Read more
Identification of Neuropeptide-gated Ion Channels in Nematode Parasites
Neurotransmitter-gated ion channels represent well-established anthelmintic targets, yet many ion channel families remain underexploited for nematode parasite… Read more
Self-funded project: Uncovering the biological roles of recently discovered carbohydrate-active enzymes in green microalgae.
Photosynthetic microalgae are microbes that have colonized every habitat on Earth, and are paramount in fueling the global ocean biological carbon pump. Read more
4-year PhD Studentship: Control of neuronal differentiation and ciliogenesis through mineralocorticoid receptor (MR) – Regulatory Factor X (RFX) interaction in embryonic and adult neurogenesis
Glucocorticoid hormones (GCs) are of critical importance for health[1]. They bind to two receptor types in the hippocampus. the mineralocorticoid (MR) and glucocorticoid receptor (GR) which act as ligand-dependent transcription factors[2-4]. Read more
Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease
Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more
De Novo Mutations and Human Disease
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more
De Novo Mutations and Human Disease
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more
Building the skull - normal and abnormal development
Using a combination of patient samples and mouse models, we study the causes and developmental origins of skull malformation. The work ranges from screening human DNA for new mutations, to use of genome editing and single cell transcriptomics to model the developmental causes of these malformations in mice. Read more
Landscape genomics and local adaptation in livestock species
Most livestock species originated in a few localities, e.g. the Fertile Crescent or the Indus Valley among others. However, today, many of those species have spread to many environments around the planet. Read more
Transcriptional control of vascular development
Sprouting of new capillaries from pre-existing vessels (angiogenesis) promotes the formation of almost all blood vessels during development, growth and tissue regeneration. Read more