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immunology PhD Projects, Programmes & Scholarships

We have 71 immunology PhD Projects, Programmes & Scholarships

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We have 71 immunology PhD Projects, Programmes & Scholarships

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How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more

Role of tumour directed T cells in smouldering myeloma

The UCL Myeloma and Tumour Immunology groups are seeking a talented and enthusiastic PhD candidate to lead a project to identify and characterise tumour directed T cells in the bone marrow environment of patients with smouldering myeloma. Smouldering myeloma is a pre-cancerous condition that carries a 50% risk (over 5 years) of developing into the bone marrow cancer called multiple myeloma. Read more

Characterisation of porcine T follicular helper cells and their response to vaccination and infection

Since they were first discovered in 2000, the function of T follicular helper (Tfh) cells has been a subject of intense and fast-moving research. It is now clear that these cells are critical in orchestrating the B cell/antibody response and they have become a focus in improving targeted cancer immunotherapy and vaccine strategies. Read more

Regulation of nuclear actin in human cancer

Actin is a cytoskeletal protein that plays essential roles in many cellular processes, such as adhesion, intracellular trafficking, membrane dynamics and motility. Read more

Immune phenotyping of refractory rheumatoid arthritis disease

Treatment of rheumatoid arthritis (RA) has been transformed with the introduction of targeted therapies twenty years ago (comprising biologic disease modifying anti-rheumatic drugs, bDMARDS; and the more recent small molecule JAK inhibitors). Read more

Self-funded BMS project: Cytokine-dependent immune cell modulation through trained immunity

Your innate immune system is the first line of defence against infections, cancer and various physiological danger signals. Innate immune dysregulation is a central driver of various pathologies ranging from neurological diseases to immunological and metabolic disorders and cancers. Read more

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