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We have 42 kinase PhD Projects, Programmes & Scholarships for Self-funded Students

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kinase PhD Projects, Programmes & Scholarships for Self-funded Students

We have 42 kinase PhD Projects, Programmes & Scholarships for Self-funded Students

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MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more
 Supervisor: Dr G Findlay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

University of York York Biomedical Research Institute
Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more
 Supervisors: Dr G Evans, Dr I Hahn
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural basis of two-component system signaling

Max Planck Institute for Chemical Ecology International Max Planck Research School
Background: . As bacteria explore new habitats, go to war with competitors or collaborate against common enemies, they rely heavily on intra- and interspecies communication and precise molecular scouting of their environment. Read more
 Supervisors: Prof UH Hellmich, Prof S.E.O. O'Connor
 18 April 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Identifying Mechanisms of Tyrosine Kinase Inhibitor Resistance in Breast/Cervical Cancer (with emphasis on FGFR)

Kingston University Faculty of Health, Science, Social Care and Education
FGF signalling is implicated in cancer (e.g., breast and cervical cancer) susceptibility and progression, suggesting that this powerful developmental pathway is co-opted by cancer cells. Read more
 Supervisor: Dr A Chioni
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MSc by Research: Monitoring and manipulating kinase activity in stem cells

University of Dundee School of Life Sciences
Posttranslational modifications of proteins are important regulatory events that impact most if not all physiological functions of cells. Read more
 Supervisor: Dr J Januschke
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis

Masaryk University Faculty of Medicine
Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. Cdk12 is transcriptional cyclin-dependent kinase (Cdk) found mutated in various cancers. Read more
 Supervisor: Dr D Blažek
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Structural and mechanistic studies of fibroblast growth factor receptor signalling

University of Leeds Faculty of Biological Sciences
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Prof A.L. Breeze, Prof F. Sobott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more
 Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The identification of allosteric inhibitors of high value therapeutic targets

University of Sheffield School of Biosciences
This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more
 Supervisor: Prof J P Waltho
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Aberrant bone morphogenetic protein signalling in precision medicine of targeting tyrosine receptor kinase in solid tumours

Cardiff University Cardiff School of Medicine
This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£55,000 total). Read more
 Supervisor: Dr L Ye
 31 May 2024  PhD Research Project  Self-Funded PhD Students Only
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Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression and tumorigenesis

Masaryk University Faculty of Medicine
Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development. Read more
 Supervisor: Dr D Blažek
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School
Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more
 Supervisors: Dr S. J. Jones, Dr M Islam
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the role(s) of Cdk1 during oocyte meiosis

University of Dundee School of Life Sciences
Meiosis is a specialised type of cell division that produces haploid daughter cells known as gametes that are important for sexual reproduction. Read more
 Supervisor: Dr F G Pelisch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more
 Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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