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mouse PhD Projects, Programmes & Scholarships
We have 98 mouse PhD Projects, Programmes & Scholarships
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Effect of Post-traumatic OA on the morphological and biomechanical properties of the mouse knee joint
Musculoskeletal diseases have a huge impact in our ageing society, affecting dramatically the disability of patients suffering from them. Read more
Evaluating the gut dysbiosis in Demented and non-Demented Parkinson’s disease patients and their effect in progressive mouse model of Parkinson’s Disease.
Dementia is not a disease rather it is a syndrome and is characterized by decrease in cognition which is noteworthy enough to alter your daily functioning. Read more
Defining the role of WT1 in cellular and molecular processes during gastrulation, in embryos and gastruloids
In an ageing population, injury and degenerative processes lead to increased pressure on the NHS due to demand on treatments. Read more
Targeting heart failure with preserved ejection fraction in settings of arthritis by modulating immune responses in a pre-clinical mouse model
Project Background. Rheumatoid arthritis (RA) patients do not die from arthritis but from complications associated with this devastating chronic disease, with cardiovascular events causing around half of all deaths in these patients [1]. Read more
PhD in Vision Sciences: Evaluating functional outcomes of novel therapies for mitochondrial optic neuropathy using ultra-high resolution multi-electrode array
Mitochondrial optic neuropathies result in blindness and are currently untreatable. They arise as a consequence of genetic mutations in either mitochondrial or nuclear DNA and share the common characteristic of primarily affecting retinal ganglion cell (RGC) survival. Read more
Towards restoring memory dysfunction in prodromal Alzheimer’s Disease.
Project outline. Brains contain billions of specialised cells, called neurons, which are the fundamental building blocks of every circuit in the nervous system. Read more
Exploring the role of matrix encapsulation on early developmental decisions using non-animal sourced hydrogels
A PhD studentship in stem cell biology and disease modelling is available in Prof Merry’s group (. https://www.nottingham.ac.uk/medicine/people/cathy.merry. Read more
Molecular mechanisms of stem cell function in skeletal muscle ageing
The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more
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Investigating the immune-stimulating effects and therapeutic potential of conjugates for antibody-mediated delivery of nucleic acid adjuvants to the tumour microenvironment
Clinical advances in tumour immunotherapy based on immune checkpoint blockade have proven that the ability of the immune system to eradicate tumours can be harnessed in the clinical setting and have reignited an interest in immunotherapies. Read more
PhD Student Position – Gene Regulation in Stem Cell Biology and Brain Development
The project will involve utilizing mouse models to dissect gene regulatory mechanisms that control neural stem cell development. Read more
Chromosome substitution strains from Chinese wild mice
Supervisors. Principal supervisor. Professor/Dr Minyan Wang…. (XJTLU). Co-supervisor. Professor/Dr Jing Zhao……...(JITRI). Read more
How do hormones regulate memory?
Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression, and impairment of memory. Read more
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
Uncovering the dynamics of SUMOylation in DNA replication
Applications are invited for a 3.5-year postgraduate studentship in the newly established SUMO biology lab in the School of Molecular and Cellular Biology, University of Leeds. Read more
The role of dynamic changes in proteome in pancreatic cancer initiation
Introduction. Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate under 7%. Better understanding of PDAC formation will help improve this. Read more