The maintenance of good muscles health provides a key aspect of general health. Reduced muscle health is associated with both ageing and a range of diseases. Read more
BACKGROUND: . In the UK, 10 million people are 65 years or older which will rise to 19 million by 2050. Ageing is characterised by immune system deterioration, inflammation and declining skeletal muscle mass and function. Read more
Primary cilia are cellular organelles present at the surface of many cell types in vertebrates. In recent years, they have been shown to play essential roles in relaying signalling information from the environment to the cell. Read more
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
Different tissues have unique genome-organisation patterns that fine-tune gene expression, e.g. by enhancing gene silencing through nuclear envelope (NE)-association. Read more
The goal of this project is to build a new model of muscle contraction called the Active Spring Muscle Model (ASMM) and to verify the model in human gait mechanics. Read more
Skeletal muscle is a vital organ supporting many physiological processes, most notably physical activity. Muscle fatigue is a physiological event defined by the inability to sustain force, but can be improved following regular exercise training. Read more
Project Description. A cyclic interaction of the filamentous proteins actin and myosin is central to muscle contraction. How this essential interaction is regulated in normal and pathophysiological states is not fully understood. Read more
A cyclic interaction of the filamentous proteins actin and myosin is central to muscle contraction. How this essential interaction is regulated in normal and pathophysiological states is not fully understood. Read more
The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more
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