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proteomic PhD Projects, Programmes & Scholarships
We have 47 proteomic PhD Projects, Programmes & Scholarships
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Developing machine learning algorithms for early detection of hepatocellular carcinoma
Primary liver cancer is the third leading cause of cancer-related death worldwide. The most common type of liver cancer is hepatocellular carcinoma (HCC), which develops in the background of liver diseases, such as cirrhosis. Read more
Proteomic analyses of adhesion signalling in cancer
Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation. Read more
Proteomic and data science analysis of polymer-protein interactions
Nanomedicine, where a therapeutic is incorporated in a nanoparticle (NP) carrier, is a promising strategy for improving clinical outcomes for a range of diseases, by improving drug efficacy through enhanced delivery to target sites. Read more
ABM CDT Spatial proteomic profiling of native human meniscus and bioprinted meniscal tissue analogues
Meniscus injuries represent a significant long-term health problem, but current treatments offer relatively poor outcomes and novel interventions are required. Read more
Approaches for the design of prostate proteomic projects and their analysis integrated with other molecular data
Research Group:
Statistical Medicine and Molecular Biology
The CRUK-funded International Cancer Genome Consortium prostate has generated whole-genome sequencing data, DNA-methylation sequencing data, mRNA expression data and small RNA data for a cohort of prostate cancer patients. Read more
Regulation of neuronal cell adhesion by a DHHC5/Golga7b palmitoyl-acyltransferase complex.
Palmitoylation (S-acylation), the only known reversible lipid modification of proteins, is an important regulator of protein localisation and function. Read more
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A Chemical Biological Platform to Interrogate the Mechanisms of Anti-Cancer Activity of Splice-Switching Small Molecules
Background. . Alternative RNA splicing is an extraordinary process that generates proteomic diversity (estimated at up to 150,000 human proteins) from only 20,000 human genes. Read more
Salivary Profile of Children and Young Adults and the Impact of Health and Lifestyle
Our population is ageing and we know that globally the number of older individuals is increasing at a greater rate than that of young people. Read more
Comparative effects of alcohol and GABA mimetics on the brain-gut-microbiota (BGM) function
Applications are invited for a fully-funded four-year PhD to commence in October 2023. . The studentship is jointly funded by the. Read more
Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
Understanding the aetiology of diabetic neuropathy
Diabetic neuropathy is a common secondary complication of diabetes mellitus which affects around 50% of all patients with diabetes - impacting on health, wellbeing and quality of life. Read more
Emerging Fraud Challenges against Alternative Proteins
The many challenges relating to environmental sustainability and climate change are major global concerns. Read more
The role of dynamic changes in proteome in pancreatic cancer initiation
Introduction. Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate under 7%. Better understanding of PDAC formation will help improve this. Read more
Proteomics-based assessment of drug performance in vivo by establishing target engagement methods and characterizing new disease models
Precise predictions of the performance of drug candidates in patients from pre-clinical systems is key for a successful drug development. Read more