Don't miss our weekly PhD newsletter | Sign up now Don't miss our weekly PhD newsletter | Sign up now

We have 52 epithelial PhD Projects, Programmes & Scholarships for Self-funded Students

Discipline

Discipline

All disciplines

Location

Location

All locations

Institution

Institution

All Institutions

PhD Type

PhD Type

All PhD Types

Funding

Funding

I am a self funded student


epithelial PhD Projects, Programmes & Scholarships for Self-funded Students

We have 52 epithelial PhD Projects, Programmes & Scholarships for Self-funded Students

How to build and maintain a 3-dimensional polarised epithelial sheet

We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more

Is there a Role for Activated Akt in Palatogenesis?

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more

Selective targeting of furin for the treatment of fibrotic lung disease.

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Unravelling the role of genotoxic E. coli in colorectal cancer (SCHULLERS_U24BIGC)

Primary supervisor - Dr Stephanie Schüller. Secondary supervisor - Prof Nathalie Juge. Colorectal cancer (CRC) is the third most common and second most fatal cancer globally. Read more

Dysfunctional antifungal potency of the respiratory mucosa in COPD

Inhalation of Aspergillus fumigatus spores cause >3,000,000 chronic and >200,000 invasive diseases annually worldwide. Invasive aspergillosis carries a 50% mortality rate overall, but mortality rate approaches 100% if diagnosis is delayed or missed and it is >75% in certain cohorts of patients, such as COPD sufferers. Read more

Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Role of mechanical signals in a 3D human model of alveolar differentiation

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

MScR: Cystic fibrosis: restoring ion transport with small molecules

Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR), a unique ATP-binding cassette transporter that functions as an ATP-gated anion channel, playing a pivotal role in salt and water movement across epithelial tissues (1). Read more

Immune regulation of lung repair, and long-term consequences of infection

This project is one of 14 four year PhD Studentships funded by Medical Research Scotland (MRS) (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO). Read more

Eliminating Harmful Cells to Maintain Homeostatis and Prevent Tumorigenesis

Hamaratoglu Lab studies cell-cell signalling in development, homeostasis and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more

SLS 1: Human lung 3D models to assess antiviral effects of novel and sustainable compounds against SARS-CoV-2 variants

We are looking for a PhD student to develop 3D models of the human breathing lung. The emergence of SARS-CoV-2 and the resulting Covid pandemic has highlighted the need for effective biological methods to assess viral infectivity and potential antiviral drug candidates. Read more

Filtering Results