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Biotechnology PhD Projects, Programs & Scholarships in Sheffield

We have 31 Biotechnology PhD Projects, Programs & Scholarships in Sheffield

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Showing 21 to 30 of 31
  Biogenesis of the Clostridium difficile cell surface
  Dr R Fagan
Applications accepted all year round

Funding Type

PhD Type

Clostridium difficile infection (CDI) is a major cause of morbidity and mortality in our hospitals. Infection normally follows disruption of the gut normal flora by broad-spectrum antibiotic treatment.
  Development of a novel immunotoxin
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

Immunotoxins represent a form of immunotherapy whereby antibodies are used to target a toxin, usually to cancer or infected host cells.
  Functional analysis of novel genes important in the physiology and pathogenesis of the human pathogen Campylobacter jejuni
  Prof D J Kelly
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni and E. coli are the commonest cause of human bacterial gastroenteritis worldwide. Although pathogenic in humans, C.
  Gliding motility in bacteria
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Motility is important for bacterial survival and facilitates colonisation and dispersal of bacteria. While swimming and type IV pili-based swarming is relatively well understood, gliding or adventurous motility, a form of surface-associated motility is still enigmatic.
  Investigating Photosynthesis in Nannochloropsis – An Important Algal Genus for Biofuel Production
  Dr D J Gilmour
Applications accepted all year round

Funding Type

PhD Type

One of the key insights from phylogenetic studies of eukaryotic microorganisms is the enormous diversity within the microalgal group with green algae being similar to plants and other groups such as diatoms being very different.
  Investigating Photosynthesis in Nannochloropsis – An Important Algal Genus for Biofuel Production
  Dr D J Gilmour
Applications accepted all year round

Funding Type

PhD Type

One of the key insights from phylogenetic studies of eukaryotic microorganisms is the enormous diversity within the microalgal group with green algae being similar to plants and other groups such as diatoms being very different.
  Optimisation of gene expression routes for heterologous protein expression in CHO cells
  Dr P Mitchell
Applications accepted all year round

Funding Type

PhD Type

CHO cells are commonly used as a vehicle for the production of heterologous proteins in the biopharmaceutical industry. We are currently using gene knock down and knock in approaches to increase the expression level of target recombinant proteins for potential use in industrial scale applications.
  Photoreceptor regulation of plant development
  Dr S Casson
Applications accepted all year round

Funding Type

PhD Type

Plant growth and development is highly dependent on the light environment. Light provides energy to drive photosynthesis but light quality and quantity is also perceived by photoreceptors, which signal to regulate responses enabling plants to adapt to their environment.
  Structural biology of the intrinsically disordered protein SH2B1
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Signalling between the outside of the cell and the inside uses a complicated network of interacting systems. One common signalling mechanism uses receptor tyrosine kinases.
  Elucidating the signalling pathways important for plasma cell biology and antibody secretion
  Dr A Peden, Dr M Collins
Applications accepted all year round

Funding Type

PhD Type

Plasma cells are the antibody secreting cells of the immune system thus are vital for fighting infection. However, dysregulation of plasma cell function is linked to a broad range of disease from Lupus to multiple myeloma.
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