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We have 18 Biotechnology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Sheffield

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Sheffield  United Kingdom

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Biotechnology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Sheffield

We have 18 Biotechnology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Sheffield

A Biotechnology PhD would provide you with the time and resources to research and develop methods and technologies that make use of Biology to improve industry. This could range from improving the efficiency of a biofuel, engineering pigment-producing bacteria to use to dye fabric, or genetically modifying crops to be resistant to a specific pest.

What’s it like to do a PhD in Biotechnology?

A PhD in Biotechnology would allow you to develop a specialist set of laboratory skills in areas such as gene editing with CRISPR and gene delivery through transformation, transfection, and transduction. Biotechnology programmes sometimes have a linked industry partner, in which case, you’ll have the opportunity to take part in a work placement and gain some hands-on industry experience.

Some typical research topics in Biotechnology include:

  • Developing therapeutic delivery vehicles
  • Engineering enzymes for industry
  • Developing or improving biofuels
  • Innovating new methods of using bacteria in industry
  • Vaccine development
  • Developing pest resistant crops

PhD programmes in Biotechnology are mostly fully-funded by either the university, an industrial partner, a doctoral training programme or a mix of these. The projects tend to be advertised, with the scope of the project determined by the supervisor.

Proposing your own project in Biotechnology is uncommon since you need to find a supervisor with research interests that overlap with yours, with all the equipment and expertise you require, and you’ll have to find funding to cover bench and PhD fees.

Day-to-day, you’ll be in the laboratory performing experiments, creating figures and analysing data you collected previously, and talking to your colleagues and supervisor about your methods and results. On completion of your laboratory work in your final year, you’ll submit an original thesis of around 60,000 words and defend this during your viva exam.

Entry requirements

The entry requirements for most Biotechnology PhD programmes involve a Masters in a subject directly related to Biology with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Biotechnology funding options

The Research Council responsible for funding Biotechnology PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s uncommon for Biotechnology PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Glycosylation in Microalgal Host Cells

Microalgae have generated increasing interest as microbial cell factories to produce therapeutics proteins. This is because they can grow on very cheap media and their GRAS (generally regarded as safe) status means they are a fantastic option for the production of therapeutics that can be administered orally. Read more

Engineering Protein Nanocompartments for Biotechnological Applications

Protein nanocompartments have board applications as catalytic nanoreactors and as carriers for therapeutics delivery. They are self-assembled protein-based supramolecules that have spherical and hollow architectures. Read more

Analysis of Oligonucleotide Therapeutics Using 2D Liquid Chromatography

We invite applications for a three and a half-year industry funded PhD studentship to work under the supervision of Prof Mark Dickman at the University of Sheffield in collaboration Dr Christina Vanhinsbergh (AstraZeneca) and Dr Ken Cook (ThermoFisher). Read more
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Serological biomarkers of aggressive multiple sclerosis

Background. The understanding of the immune pathogenesis of Multiple Sclerosis (MS) is incomplete. There is lack of clarity regarding why some patients have aggressive disease and there no reliable biomarkers to delineate this at patient’s individual level. Read more

A Melt-Electrospun Cardiac Patch for Regeneration of the Myocardium following Myocardial Infarction using Natural and Sustainable Polymers

The aim of this project is to produce a cardiac patch capable of supporting and regenerating the myocardium following myocardial infarction (MI) using melt electrospinning writing (MEW) of Poly(3-hydroxyoctanoate- co-3-hydroxydecanoate), P(3HO-co-3HD), and alginate (MEW-PHA-Alg), two natural, sustainable and highly biocompatible polymers. Read more

How does SUMOylation regulate cell survival and death in Heat Shock Response?

Heat shock response (HSR) is a universally existing essential phenomenon for all living organisms to survive sudden increases in environmental temperature that have pronounced damaging effects on important cellular structures and functions (1). Read more

Unravelling neurodevelopmental disease mechanisms of developmental delay: Additional sex combs as a model for ASXL-related disorders in the fly

Drosophila melanogaster is a fruit fly species that has been used in research for many years and are a successful model due to their superlative genetics, vast array of tools, a simple genome that is easy to alter, and the fact that 75% of human disease genes have a recognisable orthologue within flies. Read more

Novel materials for ankle ligament repair

Chronic ankle instability affects about 30% of patients who have experienced a severe ankle sprain. Around 60% of these will have degeneration of the ankle and develop osteoarthritis - a debilitating condition. Read more

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