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Cancer / Oncology PhD Projects, Programs & Scholarships in Sheffield

We have 25 Cancer / Oncology PhD Projects, Programs & Scholarships in Sheffield

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  Mechanistic Study of Molecular Assembly for Drug and Gene Delivery
  Dr X Zhao
Applications accepted all year round

Funding Type

PhD Type

Despite numerous advances over the past several decades, effective drug and gene delivery with high efficiency, low toxicity and cell targeting remains challenging.
  TRIB3 at the interface of metabolism and inflammation in adipose tissue
  Dr H Wilson, Prof E Kiss-Toth
Applications accepted all year round

Funding Type

PhD Type

Obesity drives chronic inflammation and immune activation. This results in dysregulated metabolism, insulin resistance linked to diabetes, cardiovascular disease and cancer.
  Application of data science to inherited genetic variants of apoptosis genes and susceptibility to breast cancer
  Prof A Cox, Dr K Walters
Applications accepted all year round

Funding Type

PhD Type

Background. The identification of the breast and ovarian cancer genes BRCA1 and BRCA2 two decades ago has resulted in both improved patient risk assessment and the use of PARP-inhibitors for treatment.
  Novel bone-targeted therapy for multiple myeloma
  Dr M Lawson, Dr A Chantry
Applications accepted all year round

Funding Type

PhD Type

Myeloma remains an incurable cancer despite improvements in survival outcomes over the last few years, due to the development of better therapies.
  Bacterial-derived magnetosomes as nanocarriers for cancer-killing oncolytic viruses.
  Dr M Muthana, Dr F Howard
Applications accepted all year round

Funding Type

PhD Type

Dysfunctional cellular processes that are the markers of neoplasms provide the ideal environment for viral infection including sustained proliferation and resistance to cell death.
  Evaluation of ex vivo screening methodology
  Dr S Danson, Prof T Helleday
Applications accepted all year round

Funding Type

PhD Type

Cancer affects over 14M individuals worldwide each year and in the UK only 50% of patients have a 10 year survival following cancer diagnosis.
  Exploring the role of OGG1 in fibroblast senescence
  Dr D Lambert, Prof T Helleday
Applications accepted all year round

Funding Type

PhD Type

Fibroblasts are the major cell type of connective tissue. They play a critical role in maintaining the extracellular matrix, the ‘glue’ in which most cells reside, and maintaining normal function of other types of cells such as epithelial and immune cells.
  Characterisation of in vitro models of human salivary glands and their use in functional studies
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Saliva is produced by three pairs of major salivary glands and multiple minor glands in the lips, associated with the tongue and also with the palate.
  The oral microbiome, ROS and the development of oral cancer: a role in Fanconi anemia?
  Prof K Hunter, Dr S Collis
Applications accepted all year round

Funding Type

PhD Type

Many patients with Fanconi Anemia (FA) develop cancers of the mouth, esophagus or anogential region. A number of reasons have been suggested, but the millions of bacteria that are naturally resident in these body sites might be a significant contributory factor.
  Modelling the epigenome in oral dysplasia and early invasive carcinoma
  Prof K Hunter, Dr H Colley
Applications accepted all year round

Funding Type

PhD Type

The key molecular events which lead to the development of premalignant oral lesions and their progression to oral cancer are still poorly understood.
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