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Cell Biology / Development PhD Projects, Programs & Scholarships in Sheffield

We have 41 Cell Biology / Development PhD Projects, Programs & Scholarships in Sheffield

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  Development of Intronless Expression Plasmids for Biomanufacturing of Therapeutic Proteins
  Prof S A Wilson, Dr E Thomson, Dr I Sudbery
Application Deadline: 10 January 2020

Funding Type

PhD Type

Therapeutic proteins such as antibodies are a successful class of biologic drug used to treat a wide range of diseases in areas such as oncology, respiratory, inflammation, autoimmunity and cardiology.
  University Alliance DTA3 - three-year fully-funded PhD

Funding Type

PhD Type

DTA3/COFUND offers a chance to be trained at the UK's top professional and technical universities. Operated by University Alliance, the programme is supported by the MSCA PhD programme.
  The influence of Apolipoprotein E genotypes on pathways of neurotransmission measured in vivo. Implications for dementia research
  Dr M De Marco, Prof A Venneri
Applications accepted all year round

Funding Type

PhD Type

Monoaminergic midbrain nuclei are currently emerging as major players in the definition of the pathological changes of early Alzheimer’s disease (AD) stages.
  TRIB3 at the interface of metabolism and inflammation in adipose tissue
  Dr H Wilson, Prof E Kiss-Toth
Applications accepted all year round

Funding Type

PhD Type

Obesity drives chronic inflammation and immune activation. This results in dysregulated metabolism, insulin resistance linked to diabetes, cardiovascular disease and cancer.
  Identifying inhibitors specific to the OPG-kinome: towards novel treatments for Pulmonary Arterial Hypertension (PAH).
  Prof A Lawrie, Dr R Thompson
Applications accepted all year round

Funding Type

PhD Type

Background. Pulmonary arterial hypertension (PAH) is a fatal progressive disease. Median life expectancy in untreated PAH patients is 2.8 years.
  Using the fly kidney to develop new treatments for genetic kidney diseases
  Prof A Ong, Dr N Bulgakova
Applications accepted all year round

Funding Type

PhD Type

Polycystic kidney disease is the most common hereditary cause of kidney failure in man. It comprises a spectrum of diseases of which Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common form in adults and Nephronophthisis (NPHP) the most common form in children.
  MicroRNA and Extracellular Vesicles Mediation of Embryo-Maternal Communication
  Prof A Fazeli, Dr P Heath
Applications accepted all year round

Funding Type

PhD Type

Infertility is a substantial problem affecting couples worldwide. The scars inflicted on couples as a result of not being able to conceive affects their general health, mental well-being and even raising social issues particularly in the old age.
  Exploring the role of OGG1 in fibroblast senescence
  Dr D Lambert, Prof T Helleday
Applications accepted all year round

Funding Type

PhD Type

Fibroblasts are the major cell type of connective tissue. They play a critical role in maintaining the extracellular matrix, the ‘glue’ in which most cells reside, and maintaining normal function of other types of cells such as epithelial and immune cells.
  Characterisation of in vitro models of human salivary glands and their use in functional studies
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Saliva is produced by three pairs of major salivary glands and multiple minor glands in the lips, associated with the tongue and also with the palate.
  Characterisation of the genotype and phenotype of epithelial cells invaded by the periodontal pathogen Porphyromonas gingivalis.
  Dr S Whawell, Dr G Stafford
Applications accepted all year round

Funding Type

PhD Type

The presence of the Gram negative anaerobe Porphyromonas gingivalis is consistently associated with the more severe forms of periodontal disease and its ability to invade host epithelial cells is thought to be important in the pathogenesis of the disease.
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