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Cell Biology / Development PhD Projects, Programs & Scholarships in Sheffield

We have 37 Cell Biology / Development PhD Projects, Programs & Scholarships in Sheffield

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Showing 11 to 20 of 37
  Analysis of the exoribonuclease Rex1
  Dr P Mitchell
Applications accepted all year round

Funding Type

PhD Type

Inhibition of one exosome catalytic subunit renders cells dependent upon another RNase called Rex1.
  Dissecting the mechanisms of antibiotic resistance in Clostridium difficile
  Dr R Fagan
Applications accepted all year round

Funding Type

PhD Type

Antibiotic resistance in pathogenic bacteria is one of the greatest health challenges facing humanity today.
  Optimisation of gene expression routes for heterologous protein expression in CHO cells
  Dr P Mitchell
Applications accepted all year round

Funding Type

PhD Type

CHO cells are commonly used as a vehicle for the production of heterologous proteins in the biopharmaceutical industry. We are currently using gene knock down and knock in approaches to increase the expression level of target recombinant proteins for potential use in industrial scale applications.
  Self-association of the Alzheimer’s peptide Aβ on membrane surfaces
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease is a neurodegenerative disease that is particularly common amongst the elderly. It accounts for about 65% of all cases of dementia, and affects about 6% of people over 65, rising to 50% of people over 85.
  Tetraspanin structure and function
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Reactive Inkjet Printing of Tissue Culture Scaffolds
  Dr X Zhao
Applications accepted all year round

Funding Type

PhD Type

3D scaffolds with excellent biocompatibility, biodegradability, sophisticated 3D structures and appropriate mechanical properties are particularly desired as in vitro models in biomedical research and are highly attractive in clinical applications (e.g.
  Novel therapeutic approaches for the treatment of Duchenne muscular dystrophy
  Prof S Winder
Applications accepted all year round

Funding Type

PhD Type

Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene leading to loss of the cytoskeletal protein dystrophin.
  Defining the dynamics of lineage segregations during human neuromesodermal axial progenitor differentiation
  Dr A Tsakiridis, Dr A Fletcher
Applications accepted all year round

Funding Type

PhD Type

Embryonic axis elongation is the process that gives rise to all cell types making up the body trunk.
  Developing a therapy for hearing loss using human pluripotent stem cells
  Prof M Rivolta
Applications accepted all year round

Funding Type

PhD Type

The vast majority of cases of deafness are produced by the irreversible loss of the sensory hair cells and their associated neurons.
  Elucidating the molecular function of SNAP29 a gene mutated in CEDNIK syndrome
  Dr A Peden
Applications accepted all year round

Funding Type

PhD Type

CEDNIK (cerebral dysgenesis, neuropathy, ichthyosis and keratoderma) syndrome is a rare fatal disease caused by the loss of SNAP29.
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