How does the brain encode memories? We think learning occurs by changes in the strength of synaptic connections between neurons, but the precise mechanisms by which this synaptic plasticity occurs is often unknown.
Cohn’s disease together with ulcerative colitis (UC) are the two main variations of inflammatory bowel disease (IBD). 2.5-3 million people in Europe are affected by inflammatory bowel disease with a direct healthcare cost of 4.5-6 billion Euro per year.
Reducing food intake robustly increases lifespan in model organisms. When this data is extrapolated to humans, the predicted gain in healthy lifespan beats curing all stroke, diabetes, cancer and cardiac disease.