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We have 29 Genetics PhD Projects, Programmes & Scholarships in Sheffield
Genetics PhD Projects, Programmes & Scholarships in Sheffield
We have 29 Genetics PhD Projects, Programmes & Scholarships in Sheffield
Investigation of the biological behaviour and genetic regulation of rare cancers, to develop new therapies.
We are an active research group investigating ocular tumours, sarcomas, and have an interest in thyroid cancer. Currently we have five PhD students who are in various stages of their study. Read more
ACCE+ DLA programme - EpiPlasticity: exploring the ecological and evolutionary significance of epigenetic defence plasticity
The ACCE+ DLA is committed to recruiting extraordinary future scientists regardless of age, disability, ethnicity, gender, gender identity, sexual orientation, faith or religious belief, pregnancy or maternity, parental or caring responsibilities or career pathway to date. Read more
ACCE+ DLA programme - Can microrefugia buffer threatened species from climate change?
The ACCE+ DLA is committed to recruiting extraordinary future scientists regardless of age, disability, ethnicity, gender, gender identity, sexual orientation, faith or religious belief, pregnancy or maternity, parental or caring responsibilities or career pathway to date. Read more
MRC DiMeN Doctoral Training Partnership: Getting to the heart of cardiac infection using zebrafish models
Inflammatory heart diseases are major causes of mortality worldwide and often result from infections in the heart. Staphylococci bacteria frequently infect the heart from bloodstream infections, yet the cellular and molecular mechanisms underlying this are poorly understood. Read more
The MRC Discovery Medicine North (DiMeN) Doctoral Training Partnership is offering up to 42 fully funded studentships, with a start date of October 2025
These four-year studentships are open to both home and overseas fee status applicants. Stipend is provided at the UKRI standard rate and fees are covered for all students. Read more
MRC DiMeN Doctoral Training Partnership: A search for pharmacological inhibitors of a cancer-associated adhesion GPCR in the zebrafish embryo
Adhesion GPCRs have exciting potential as therapeutic targets for drug discovery. The focus of this PhD project is on ADGRG6 (GPR126), an adhesion class G-protein-coupled receptor (aGPCR) of considerable clinical interest. Read more
MRC DiMeN Doctoral Training Partnership: Why do multiple pathogenic viruses including HIV, Influenza, Ebola, Herpesviruses and Adenovirus target a host RNA binding protein?
Viruses frequently hijack cellular processes as part of their life cycle. A recent proteomics screen revealed a core of mammalian proteins which are targeted by multiple viruses, defining four critical cellular nodes in viral infections (Viral immune modulators perturb the human molecular network by. Read more
MRC DiMeN Doctoral Training Partnership: Understanding the mechanisms associated with mitochondria dysfunction underpinning both age-related hearing loss and neurodegenerative diseases.
Age-related hearing loss (ARHL) is the most common sensory deficits in humans and one of the most prevalent chronic dysfunctions in older adults. Read more
MRC DiMeN Doctoral Training Partnership: Tackling ageing in the gut: investigating the contribution of macrophages in the intestinal stem cell niche to gut maintenance and repair.
Ageing of the gut is an important contributor to multimorbidity of the elderly, including frailty, and mental decline. However, the specific cellular and molecular mechanisms driving gut degeneration with ageing and how these lead to specific clinical outcomes are still unclear. Read more
MRC DiMeN Doctoral Training Partnership: Examining the role of metabolism in paediatric cancer initiation using human pluripotent stem cells
Neuroblastoma (NB) is the most common extracranial solid tumor in infants, arising from the oncogenic transformation of trunk neural crest (NC) cells—multipotent embryonic cells that develop into the adrenal gland and sympathetic neurons. Read more
The role of endothelial PKD1 in endothelial dysfunction and formation of aortic aneurysms
Polycytin-1 (PKD1) is the main causative gene for autosomal dominant polycystic kidney disease (ADPKD) affecting every 1 in 400 to 1,000 people. Read more
How well can mice reproduce human frailty?
We are living longer but not necessarily healthier. One condition that affect older people is frailty, which makes people vulnerable to stressors such as infections or falls in a much more profound way than younger people. Read more
Efficacy of novel antimicrobial treatments on oral pathogens
Project details. Bacterial oral infections can cause a variety of problems including dental caries, abscesses, gingivitis and periodontal disease. Read more
Population genomics of insect communities
Declines in insect populations and species are arguably one of the most concerning symptoms of the biodiversity crisis, given their importance in underpinning food webs and ecosystem processes. Read more
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